PMID- 26246311
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20190207
IS  - 1476-5527 (Electronic)
IS  - 0950-9240 (Print)
IS  - 0950-9240 (Linking)
VI  - 30
IP  - 3
DP  - 2016 Mar
TI  - Uncontrolled blood pressure and risk of sleep apnea among blacks: findings from 
      the Metabolic Syndrome Outcome (MetSO) study.
PG  - 149-52
LID - 10.1038/jhh.2015.78 [doi]
AB  - Uncontrolled blood pressure (BP) is linked to increased risk of obstructive sleep 
      apnea (OSA). However, few studies have assessed the impact of this relationship 
      among blacks with metabolic syndrome (MetS). Data for this study were collected 
      from 1035 blacks (mean age=62+/-13 years) enrolled in the Metabolic Syndrome 
      Outcome study. Patients with a score ⩾6 on the Apnea Risk Evaluation System were 
      considered at risk for OSA. Of the sample, 77.1% were low-to-high OSA risk and 
      92.3% were hypertensive, of which 16.8% had uncontrolled BP levels. Analysis also 
      showed that 60.4% were diabetic, 8.9% had a stroke history, 74.3% had 
      dyslipidemia, 69.8% were obese and 30.9% had a history of heart disease. Logistic 
      regression analyses were employed to investigate associations between 
      uncontrolled BP and OSA risk, while adjusting for known covariates. Findings 
      showed that uncontrolled BP independently increased the odds of OSA risk twofold 
      (odds ratio=2.02, 95% confidence interval=1.18-3.48, P<0.05). In conclusion, our 
      findings show that uncontrolled BP was associated with a twofold greater risk of 
      OSA among blacks, suggesting that those with MetS and who have uncontrolled BP 
      should be screened for the presence of OSA.
FAU - Seixas, A
AU  - Seixas A
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
FAU - Ravenell, J
AU  - Ravenell J
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
FAU - Williams, N J
AU  - Williams NJ
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
FAU - Williams, S K
AU  - Williams SK
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
FAU - Zizi, F
AU  - Zizi F
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
FAU - Ogedegbe, G
AU  - Ogedegbe G
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
FAU - Jean-Louis, G
AU  - Jean-Louis G
AD  - Center for Healthful Behavior Change, Department of Population Health, New York 
      University School of Medicine, New York, NY, USA.
LA  - eng
GR  - R01MD007716/MD/NIMHD NIH HHS/United States
GR  - K24 HL111315/HL/NHLBI NIH HHS/United States
GR  - R01MD004113/MD/NIMHD NIH HHS/United States
GR  - U54 NS081765/NS/NINDS NIH HHS/United States
GR  - R01 MD007716/MD/NIMHD NIH HHS/United States
GR  - R01 MD004113/MD/NIMHD NIH HHS/United States
GR  - K07 AG052685/AG/NIA NIH HHS/United States
GR  - U54NS081765/NS/NINDS NIH HHS/United States
GR  - K24HL111315/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20150806
PL  - England
TA  - J Hum Hypertens
JT  - Journal of human hypertension
JID - 8811625
SB  - IM
MH  - Aged
MH  - Blood Pressure
MH  - Cohort Studies
MH  - Female
MH  - Humans
MH  - Hypertension/*complications
MH  - Male
MH  - Metabolic Syndrome/*complications
MH  - Middle Aged
MH  - New York/epidemiology
MH  - Sleep Apnea, Obstructive/*ethnology/etiology
PMC - PMC4744577
MID - NIHMS681585
COIS- CONFLICT OF INTEREST All coauthors meet the criteria for authorship, including 
      acceptance of responsibility for the scientific content of the paper. They have 
      seen and agreed on the contents of the paper and there is no financial conflict 
      or conflicts of interests to report. They certify that the submission is the 
      original work and is not under review at any other publication.
EDAT- 2015/08/08 06:00
MHDA- 2016/12/15 06:00
PMCR- 2016/05/18
CRDT- 2015/08/07 06:00
PHST- 2014/10/17 00:00 [received]
PHST- 2015/03/30 00:00 [revised]
PHST- 2015/04/14 00:00 [accepted]
PHST- 2015/08/07 06:00 [entrez]
PHST- 2015/08/08 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
PHST- 2016/05/18 00:00 [pmc-release]
AID - jhh201578 [pii]
AID - 10.1038/jhh.2015.78 [doi]
PST - ppublish
SO  - J Hum Hypertens. 2016 Mar;30(3):149-52. doi: 10.1038/jhh.2015.78. Epub 2015 Aug 
      6.