PMID- 26250591
OWN - NLM
STAT- MEDLINE
DCOM- 20170711
LR  - 20210703
IS  - 1742-481X (Electronic)
IS  - 1742-4801 (Print)
IS  - 1742-4801 (Linking)
VI  - 13
IP  - 5
DP  - 2016 Oct
TI  - Patients with pyoderma gangrenosum - analyses of the German DRG data from 2012.
PG  - 951-6
LID - 10.1111/iwj.12463 [doi]
AB  - Pyoderma gangrenosum (PG) is a rarely diagnosed non-infectious neutrophil 
      ulcerative dermatosis with only limited knowledge on the underlying 
      auto-inflammatory process. To unravel common cofactors and comorbidities in 
      patients with PG we analysed Diagnosis Related Groups (DRG) cases of all 
      inpatients diagnosed with PG in German hospitals in 2012. We received data of 
      1227 inpatient cases having PG as primary diagnosis and 985 inpatient cases with 
      PG as secondary diagnosis. The ratio of women to men was 2:1, and the most often 
      registered age was 75-79 years. Common comorbidities were arterial hypertension 
      (50.3%), non-insulin-dependent diabetes mellitus (25.1%) and dysfunction of lipid 
      metabolism (10.8%). In sum, 94.8% of the patients suffered from aspects of 
      metabolic syndrome. Other comorbidities were Crohn's disease (4.5%), ulcerative 
      colitis (4.2%), chronic polyarthritis (5.2%), monoclonal gammopathy or 
      myelodysplastic syndrome (2.5%), leukaemia (1.1%) and lymphoma (0.4%). DRG data 
      do not reflect individual patients, but rather patient cases. We described the 
      worldwide largest PG population and confirmed a wide range of potentially 
      relevant and partly not yet described cofactors and comorbidities such as 
      metabolic syndrome.
CI  - (c) 2015 Medicalhelplines.com Inc and John Wiley & Sons Ltd.
FAU - Jockenhofer, Finja
AU  - Jockenhofer F
AD  - Department of Dermatology, Venerology and Allergology, University Hospital of 
      Medicine, Essen, Germany.
FAU - Klode, Joachim
AU  - Klode J
AD  - Department of Dermatology, Venerology and Allergology, University Hospital of 
      Medicine, Essen, Germany.
FAU - Kroger, Knut
AU  - Kroger K
AD  - Department of Vascular Medicine, Helios Hospital, Krefeld, Germany.
FAU - Roesch, Alexander
AU  - Roesch A
AD  - Department of Dermatology, Venerology and Allergology, University Hospital of 
      Medicine, Essen, Germany.
FAU - Al Ghazal, Philipp
AU  - Al Ghazal P
AD  - Department of Dermatology, Venereology and Allergology, University Medical Center 
      Gottingen, Gottingen, Germany.
FAU - Dissemond, Joachim
AU  - Dissemond J
AD  - Department of Dermatology, Venerology and Allergology, University Hospital of 
      Medicine, Essen, Germany. joachim.dissemond@uk-essen.de.
LA  - eng
PT  - Journal Article
DEP - 20150806
PL  - England
TA  - Int Wound J
JT  - International wound journal
JID - 101230907
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Child
MH  - Child, Preschool
MH  - Diagnosis-Related Groups
MH  - Female
MH  - Germany/epidemiology
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Pyoderma Gangrenosum/complications/diagnosis/*epidemiology
MH  - Sex Distribution
MH  - Young Adult
PMC - PMC7949574
OTO - NOTNLM
OT  - Chronic wounds
OT  - Comorbidities
OT  - German Federal Statistical Office
OT  - Metabolic syndrome
OT  - Pyoderma gangrenosum
EDAT- 2015/08/08 06:00
MHDA- 2017/07/14 06:00
PMCR- 2015/08/06
CRDT- 2015/08/08 06:00
PHST- 2015/03/11 00:00 [received]
PHST- 2015/04/19 00:00 [revised]
PHST- 2015/04/20 00:00 [accepted]
PHST- 2015/08/08 06:00 [entrez]
PHST- 2015/08/08 06:00 [pubmed]
PHST- 2017/07/14 06:00 [medline]
PHST- 2015/08/06 00:00 [pmc-release]
AID - IWJ12463 [pii]
AID - 10.1111/iwj.12463 [doi]
PST - ppublish
SO  - Int Wound J. 2016 Oct;13(5):951-6. doi: 10.1111/iwj.12463. Epub 2015 Aug 6.