PMID- 26252343 OWN - NLM STAT- MEDLINE DCOM- 20160831 LR - 20151029 IS - 1932-751X (Electronic) IS - 1932-7501 (Linking) VI - 35 IP - 6 DP - 2015 Nov-Dec TI - Field Walking Tests Are Reliable and Responsive to Exercise Training in People With Non-Cystic Fibrosis Bronchiectasis. PG - 439-45 LID - 10.1097/HCR.0000000000000130 [doi] AB - PURPOSE: The 6-Minute Walk Test (6MWT) and Incremental Shuttle Walk Test (ISWT) are used to assess exercise capacity, but the reliability and responsiveness of these tests in individuals with non-cystic fibrosis (CF) bronchiectasis have not been determined. This study aimed to determine the reliability and responsiveness of both tests in adults with non-CF bronchiectasis. METHODS: Eighty-five participants completed 2 6MWTs and 2 ISWTs in random order. Testing was repeated at the conclusion of an 8-week intervention period of exercise training. Reliability was assessed using intraclass correlation coefficients (ICC) and Bland-Altman analysis. Responsiveness was measured by effect size (ES) and standardized response mean (SRM). RESULTS: At baseline, test-retest reliability was high for both tests (ICC >/= 0.95). The mean (95% CI) increase in the 6MWT from test 1 to test 2 was 20 m (13-26 m): 3% (0-5%) change. The mean (95% CI) increase in the ISWT was 15 m (4-25m): 4% (2-6%) change. A significant learning effect persisted after 8 weeks for the 6MWT (P = .04), but not the ISWT (P = .61). The 6MWT ES was 0.32 and SRM was 0.68; for the ISWT, ES was 0.42 with SRM of 0.71. CONCLUSION: The 6MWT and ISWT are reliable measures of exercise capacity in non-CF bronchiectasis and responsive to exercise training. The small learning effect in both measures at baseline suggests that 2 of each test are necessary to correctly assess exercise capacity. Completion of 2 6MWTs at followup may minimize the risk of underestimating a treatment effect. FAU - Lee, Annemarie L AU - Lee AL AD - Physiotherapy, Alfred Health (Drs Lee and Holland and Ms Burge), Physiotherapy, La Trobe University (Dr Holland), and Allergy, Immunology and Respiratory Medicine, Alfred Health (Dr Stirling), Melbourne, Victoria, Australia; Institute for Breathing and Sleep (Drs Lee, Holland, Hill, and McDonald and Ms Rautela), Physiotherapy (Dr Hill and Ms Rautela), and Respiratory and Sleep Medicine (Dr McDonald), Austin Health, Heidelberg, Victoria, Australia; Physiotherapy, Sir Charles Gairdner Hospital (Ms Cecins and Dr Jenkins), Lung Institute of Western Australia (Ms Cecins and Drs Thompson and Jenkins), and Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital (Dr Thompson), Nedlands, Western Australia, Australia; and Community Physiotherapy Services (Ms Cecins) and Physiotherapy and Exercise Science, Curtin University (Drs Thompson and Jenkins), Perth, Western Australia, Australia. FAU - Cecins, Nola AU - Cecins N FAU - Holland, Anne E AU - Holland AE FAU - Hill, Catherine J AU - Hill CJ FAU - McDonald, Christine F AU - McDonald CF FAU - Burge, Angela T AU - Burge AT FAU - Rautela, Linda AU - Rautela L FAU - Thompson, Philip J AU - Thompson PJ FAU - Stirling, Robert G AU - Stirling RG FAU - Jenkins, Sue AU - Jenkins S LA - eng SI - ClinicalTrials.gov/NCT00885521 PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Cardiopulm Rehabil Prev JT - Journal of cardiopulmonary rehabilitation and prevention JID - 101291247 SB - IM MH - Bronchiectasis/*physiopathology/*rehabilitation MH - Exercise Test/*statistics & numerical data MH - Exercise Tolerance/*physiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Oxygen Consumption/*physiology MH - Reproducibility of Results MH - Walking EDAT- 2015/08/08 06:00 MHDA- 2016/09/01 06:00 CRDT- 2015/08/08 06:00 PHST- 2015/08/08 06:00 [entrez] PHST- 2015/08/08 06:00 [pubmed] PHST- 2016/09/01 06:00 [medline] AID - 10.1097/HCR.0000000000000130 [doi] PST - ppublish SO - J Cardiopulm Rehabil Prev. 2015 Nov-Dec;35(6):439-45. doi: 10.1097/HCR.0000000000000130.