PMID- 26258625
OWN - NLM
STAT- MEDLINE
DCOM- 20160805
LR  - 20191210
IS  - 1879-0771 (Electronic)
IS  - 0895-6111 (Linking)
VI  - 45
DP  - 2015 Oct
TI  - Intravascular ultrasonic-photoacoustic (IVUP) endoscope with 2.2-mm diameter 
      catheter for medical imaging.
PG  - 57-62
LID - S0895-6111(15)00106-8 [pii]
LID - 10.1016/j.compmedimag.2015.07.008 [doi]
AB  - Intravascular ultrasound (IVUS) imaging is extremely important for detection and 
      characterization of high-risk atherosclerotic plaques as well as gastrointestinal 
      diseases. Recently, intravascular photoacoustic (IVPA) imaging has been used to 
      differentiate the composition of biological tissues with high optical contrast 
      and ultrasonic resolution. The combination of these imaging techniques could 
      provide morphological information and molecular screening to characterize 
      abnormal tissues, which would help physicians to ensure vital therapeutic value 
      and prognostic significance for patients before commencing therapy. In this 
      study, integration of a high-frequency IVUS imaging catheter (45MHz, 
      single-element, unfocused, 0.7mm in diameter) with a multi-mode optical fiber 
      (0.6mm in core diameter, 0.22 NA), an integrated intravascular 
      ultrasonic-photoacoustic (IVUP) imaging catheter, was developed to provide 
      spatial and functional information on light distribution in a turbid sample. 
      Simultaneously, IVUS imaging was co-registered to IVPA imaging to construct 3D 
      volumetric sample images. In a phantom study, a polyvinyl alcohol (PVA) 
      tissue-mimicking arterial vessel phantom with indocyanine green (ICG) and 
      methylene blue (MB) inclusion was used to demonstrate the feasibility of mapping 
      the biological dyes, which are used in cardiovascular and cancer diagnostics. For 
      the ex vivo study, an excised sample of pig intestine with ICG was utilized to 
      target the biomarkers present in the gastrointestinal tumors or the 
      atherosclerotic plaques with the proposed hybrid technique. The results indicated 
      that IVUP endoscope with the 2.2-mm diameter catheter could be a useful tool for 
      medical imaging.
CI  - Copyright (c) 2015 Elsevier Ltd. All rights reserved.
FAU - Bui, Nhat Quang
AU  - Bui NQ
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea.
FAU - Hlaing, Kyu Kyu
AU  - Hlaing KK
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea.
FAU - Nguyen, Van Phuc
AU  - Nguyen VP
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea.
FAU - Nguyen, Trung Hau
AU  - Nguyen TH
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea.
FAU - Oh, Yun-Ok
AU  - Oh YO
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea.
FAU - Fan, Xiao Feng
AU  - Fan XF
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea.
FAU - Lee, Yong Wook
AU  - Lee YW
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea; School of Electrical 
      Engineering, Pukyong National University, Busan, South Korea.
FAU - Nam, Seung Yun
AU  - Nam SY
AD  - Department of Biomedical Engineering, Pukyong National University, Busan, South 
      Korea.
FAU - Kang, Hyun Wook
AU  - Kang HW
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea; Department of Biomedical 
      Engineering, Pukyong National University, Busan, South Korea.
FAU - Oh, Junghwan
AU  - Oh J
AD  - Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, 
      Pukyong National University, Busan, South Korea; Department of Biomedical 
      Engineering, Pukyong National University, Busan, South Korea. Electronic address: 
      jungoh@pknu.ac.kr.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20150722
PL  - United States
TA  - Comput Med Imaging Graph
JT  - Computerized medical imaging and graphics : the official journal of the 
      Computerized Medical Imaging Society
JID - 8806104
SB  - IM
MH  - Animals
MH  - *Catheters
MH  - Elasticity Imaging Techniques/*instrumentation
MH  - Endosonography/*instrumentation
MH  - Equipment Design
MH  - Equipment Failure Analysis
MH  - Imaging, Three-Dimensional/*instrumentation
MH  - Miniaturization
MH  - Multimodal Imaging/instrumentation
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Subtraction Technique/*instrumentation
MH  - Swine
MH  - Ultrasonography, Interventional/*instrumentation
OTO - NOTNLM
OT  - 3D reconstruction
OT  - Combined imaging
OT  - Imaging endoscope
OT  - Indocyanine green
OT  - Intravascular photoacoustic imaging
OT  - Intravascular ultrasound imaging
EDAT- 2015/08/11 06:00
MHDA- 2016/08/06 06:00
CRDT- 2015/08/11 06:00
PHST- 2015/01/21 00:00 [received]
PHST- 2015/06/11 00:00 [revised]
PHST- 2015/07/13 00:00 [accepted]
PHST- 2015/08/11 06:00 [entrez]
PHST- 2015/08/11 06:00 [pubmed]
PHST- 2016/08/06 06:00 [medline]
AID - S0895-6111(15)00106-8 [pii]
AID - 10.1016/j.compmedimag.2015.07.008 [doi]
PST - ppublish
SO  - Comput Med Imaging Graph. 2015 Oct;45:57-62. doi: 
      10.1016/j.compmedimag.2015.07.008. Epub 2015 Jul 22.