PMID- 2626137 OWN - NLM STAT- MEDLINE DCOM- 19900404 LR - 20061115 IS - 0300-5283 (Print) IS - 0300-5283 (Linking) VI - 44 IP - 3 DP - 1989 Sep TI - Hyperthyroid graves disease--a 5 year retrospective study. PG - 224-30 AB - The clinical, biochemical and immunological features of 180 patients with hyperthyroid Graves' disease managed at the Universiti Kebangsaan Malaysia (UKM) Endocrine Clinic from 1983 to 1987 were examined. The prevalence of the disease is highest in Chinese and lowest in Indians. The female: male ratio is 2.8:1. Hypokalaemic periodic paralysis and hypercalcaemia were present in 5.0% and 1.7% of the cases respectively. Pretibial myxoedema was extremely rare. Thyrotropin - binding inhibitory immunoglobulins, anti-thyroglobulin and anti-microsome antibodies were positive in 61.5%, 25.8% and 42.3% of the patients respectively. A eumetabolic state could be achieved in the majority of patients with antithyroid drugs alone. Definitive therapy with subtotal thyroidectomy or radioiodine were needed in 31.3% of cases. FAU - Tan, T T AU - Tan TT FAU - Ng, M L AU - Ng ML FAU - Wu, L L AU - Wu LL FAU - Khalid, B A AU - Khalid BA LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Malaysia TA - Med J Malaysia JT - The Medical journal of Malaysia JID - 0361547 SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Child MH - Female MH - Graves Disease/*diagnosis/epidemiology/therapy MH - Humans MH - Malaysia/epidemiology MH - Male MH - Middle Aged MH - Retrospective Studies EDAT- 1989/09/01 00:00 MHDA- 1989/09/01 00:01 CRDT- 1989/09/01 00:00 PHST- 1989/09/01 00:00 [pubmed] PHST- 1989/09/01 00:01 [medline] PHST- 1989/09/01 00:00 [entrez] PST - ppublish SO - Med J Malaysia. 1989 Sep;44(3):224-30.