PMID- 26265055 OWN - NLM STAT- MEDLINE DCOM- 20160509 LR - 20211203 IS - 1399-0039 (Electronic) IS - 0001-2815 (Linking) VI - 86 IP - 3 DP - 2015 Sep TI - HLA alleles and haplotypes in Burmese (Myanmarese) and Karen in Thailand. PG - 199-204 LID - 10.1111/tan.12637 [doi] AB - This is the first report on human leukocyte antigen (HLA) allele and haplotype frequencies at three class I loci and two class II loci in unrelated healthy individuals from two ethnic groups, 170 Burmese and 200 Karen, originally from Burma (Myanmar), but sampled while residing in Thailand. Overall, the HLA allele and haplotype frequencies detected by polymerase chain reaction sequence-specific primer (PCR-SSP) at five loci (A, B, C, DRB1 and DRQB1) at low resolution showed distinct differences between the Burmese and Karen. In Burmese, five HLA-B*15 haplotypes with different HLA-A and HLA-DR/DQ combinations were detected with three of these not previously reported in other Asian populations. The data are important in the fields of anthropology, transplantation and disease-association studies. CI - (c) 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. FAU - Kongmaroeng, C AU - Kongmaroeng C AD - Department of Blood Bank, Faculty of Medical Technology, Huachiew Chalermprakiet University, Samut Prakarn, Thailand. FAU - Romphruk, A AU - Romphruk A AD - Department of Clinical Immunology and Transfusion Sciences, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. AD - The Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. FAU - Puapairoj, C AU - Puapairoj C AD - Blood Transfusion Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. FAU - Leelayuwat, C AU - Leelayuwat C AD - Department of Clinical Immunology and Transfusion Sciences, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. AD - The Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. FAU - Kulski, J K AU - Kulski JK AD - Centre for Forensic Science, The University of Western Australia, Nedlands, Australia. FAU - Inoko, H AU - Inoko H AD - Department of Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine, Tokyo, Japan. FAU - Dunn, D S AU - Dunn DS AD - Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia. FAU - Romphruk, A V AU - Romphruk AV AD - The Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. AD - Blood Transfusion Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Tissue Antigens JT - Tissue antigens JID - 0331072 RN - 0 (Histocompatibility Antigens Class I) SB - IM MH - *Alleles MH - Ethnicity/*genetics MH - Gene Frequency/genetics MH - Genetic Loci MH - Haplotypes/genetics MH - Histocompatibility Antigens Class I/*genetics MH - Humans MH - Linkage Disequilibrium/genetics MH - Myanmar MH - Thailand OTO - NOTNLM OT - Burmese OT - Karen OT - Southeast Asian OT - haplotype frequency OT - human leukocyte antigen EDAT- 2015/08/13 06:00 MHDA- 2016/05/10 06:00 CRDT- 2015/08/13 06:00 PHST- 2015/01/03 00:00 [received] PHST- 2015/06/02 00:00 [revised] PHST- 2015/07/14 00:00 [accepted] PHST- 2015/08/13 06:00 [entrez] PHST- 2015/08/13 06:00 [pubmed] PHST- 2016/05/10 06:00 [medline] AID - 10.1111/tan.12637 [doi] PST - ppublish SO - Tissue Antigens. 2015 Sep;86(3):199-204. doi: 10.1111/tan.12637.