PMID- 26266696
OWN - NLM
STAT- MEDLINE
DCOM- 20160629
LR  - 20151002
IS  - 1557-8976 (Electronic)
IS  - 0882-8245 (Linking)
VI  - 28
IP  - 8
DP  - 2015 Oct
TI  - Erythema Multiforme Associated with Respiratory Disease in a Commercial Breeding 
      Pig Herd.
PG  - 464-71
LID - 10.1089/vim.2015.0063 [doi]
AB  - This study describes an erythema multiforme (EM) in breeding sows, after their 
      mixing in the group housing system. Sows at 30-35 days of gestation showed red 
      and raised skin areas, depression, anorexia, fever, respiratory problems, and 
      increased return to estrus. Blood and nasal samples from diseased sows were 
      examined by quantitative polymerase chain reaction and enzyme-linked 
      immunosorbent assay for respiratory pathogens. Hematological and biochemical 
      analyses were performed on the blood samples. From diseased sows, vaginal swabs 
      for microbiological examinations and samples at slaughterhouse for gross and 
      microscopic examinations were collected. Samples from the complete gestation and 
      lactation feed were examined for mycotoxins. All sampled sows were seropositive 
      for Actinobacillus pleuropneumoniae (App) and porcine reproductive and 
      respiratory syndrome virus (PRRSV). No viremia for PRRSV and porcine circovirus 
      type 2 were detected. All nasal samples were positive for Streptococcus suis, one 
      for Swine Influenza Virus and one for App, Hemophilus parasuis, and S. suis. In 
      all vaginal swabs, Escherichia coli and Streptococcus spp. were detected. 
      Diseased sows had moderate leukocytosis, mild anemia, and thrombocytopenia. No 
      mycotoxins were detected in feed. Histopathological examination revealed 
      increased vascularization of the superficial and middle dermis. EM was likely due 
      to illness caused by viral and bacterial infections. This study suggests that 
      stress caused by the sows' mixing might have triggered the problem.
FAU - Papatsiros, Vasileios G
AU  - Papatsiros VG
AD  - 1 Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly , 
      Karditsa, Greece .
FAU - Athanasiou, Labrini V
AU  - Athanasiou LV
AD  - 1 Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly , 
      Karditsa, Greece .
FAU - Psalla, Dimitra
AU  - Psalla D
AD  - 2 Laboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University 
      of Thessaloniki , Thessaloniki, Greece .
FAU - Petridou, Evanthia
AU  - Petridou E
AD  - 3 Laboratory of Microbiology and Infectious Diseases, Faculty of Veterinary 
      Medicine, Aristotle University of Thessaloniki , Thessaloniki, Greece .
FAU - Maragkakis, Giorgos G
AU  - Maragkakis GG
AD  - 1 Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly , 
      Karditsa, Greece .
FAU - Papatsas, Ioannis
AU  - Papatsas I
AD  - 4 Altavet EE, Farm Animal Department , Thessaloniki, Greece .
FAU - Arsenakis, Ioannis
AU  - Arsenakis I
AD  - 5 Department of Reproduction, Obstetrics, and Herd Health Unit Porcine Health 
      Management, Faculty of Veterinary Medicine, Ghent University , Ghent, Belgium .
FAU - Maes, Dominiek
AU  - Maes D
AD  - 5 Department of Reproduction, Obstetrics, and Herd Health Unit Porcine Health 
      Management, Faculty of Veterinary Medicine, Ghent University , Ghent, Belgium .
LA  - eng
PT  - Journal Article
DEP - 20150812
PL  - United States
TA  - Viral Immunol
JT  - Viral immunology
JID - 8801552
SB  - IM
MH  - Animals
MH  - Bacteria/isolation & purification
MH  - Erythema Multiforme/complications/epidemiology/pathology/*veterinary
MH  - Female
MH  - Histocytochemistry
MH  - Microscopy
MH  - Porcine respiratory and reproductive syndrome virus/isolation & purification
MH  - Respiratory Tract Diseases/epidemiology/pathology/*veterinary
MH  - Swine
MH  - Swine Diseases/diagnosis/*epidemiology/*pathology
EDAT- 2015/08/13 06:00
MHDA- 2016/06/30 06:00
CRDT- 2015/08/13 06:00
PHST- 2015/08/13 06:00 [entrez]
PHST- 2015/08/13 06:00 [pubmed]
PHST- 2016/06/30 06:00 [medline]
AID - 10.1089/vim.2015.0063 [doi]
PST - ppublish
SO  - Viral Immunol. 2015 Oct;28(8):464-71. doi: 10.1089/vim.2015.0063. Epub 2015 Aug 
      12.