PMID- 26273701 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240323 IS - 2377-1372 (Print) IS - 2377-1372 (Electronic) IS - 2377-1372 (Linking) VI - 2 IP - 2 DP - 2015 Sep 7 TI - Comparison of Simulated Workplace Protection Factors Offered by N95 and P100 Filtering Facepiece and Elastomeric Half-Mask Respirators against Particles of 10 to 400 nm. PG - 1-6 AB - This study compared the simulated workplace protection factors (SWPFs) between NIOSH-approved N95 respirators and P100 respirators, including two models of filtering facepiece respirator (FFR) and two models of elastomeric half-mask respirator (EHR), against sodium chloride particles (NaCl) in a range of 10 to 400 nm. Twenty-five human test subjects performed modified OSHA fit test exercises in a controlled laboratory environment with the N95 respirators (two FFR models and two EHR models) and the P100 respirators (two FFRs and two EHRs). Two Scanning Mobility Particle Sizers (SMPS) were used to measure aerosol concentrations (in the 10-400 nm size range) inside (C(in)) and outside (C(out)) of the respirator, simultaneously. SWPF was calculated as the ratio of C(out) to C(in). The SWPF values obtained from the N95 respirators were then compared to those of the P100 respirators. SWPFs were found to be significantly different (P<0.05) between N95 and P100 class respirators. The 10(th), 25(th), 50(th), 75(th) and 90(th) percentiles of the SWPFs for the N95 respirators were much lower than those for the P100 models. The N95 respirators had 5(th) percentiles of the SWPFs > 10. In contrast, the P100 class was able to generate 5(th) percentiles SWPFs > 100. No significant difference was found in the SWPFs when tested against nano-size (10 to 100 nm) and large-size (100 to 400 nm) particles. Overall, the findings suggest that the two FFRs and two EHRs with P100 class filters provide better performance than those with N95 filters against particles from 10 to 400 nm, supporting current OSHA and NIOSH recommendations. FAU - He, Xinjian AU - He X AD - National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA ; Industrial and Management Systems Engineering, College of Engineering and Mineral Resources, West Virginia University, Morgantown, WV. FAU - Vo, Evanly AU - Vo E AD - National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA. FAU - Horvatin, M AU - Horvatin M AD - URS, Inc. Pittsburgh, PA. FAU - Liu, Y AU - Liu Y AD - National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA ; Institute of Health Surveillance, Analysis and Protection, Hubei Center for Disease Control and Prevention, Wuhan, Hubei, China. FAU - Bergman, M AU - Bergman M AD - National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA. FAU - Zhuang, Z AU - Zhuang Z AD - National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA. LA - eng GR - CC999999/Intramural CDC HHS/United States PT - Journal Article PL - United States TA - J Nanotechnol Mater Sci JT - Journal of nanotechnology and materials science JID - 101664422 PMC - PMC4529391 MID - NIHMS709765 OTO - NOTNLM OT - FFR OT - HER OT - N95 OT - Nano particle OT - P100 OT - Respirator OT - SWPF EDAT- 2015/08/15 06:00 MHDA- 2015/08/15 06:01 PMCR- 2015/09/07 CRDT- 2015/08/15 06:00 PHST- 2015/08/15 06:00 [entrez] PHST- 2015/08/15 06:00 [pubmed] PHST- 2015/08/15 06:01 [medline] PHST- 2015/09/07 00:00 [pmc-release] AID - 10.15436/2377-1372.15.015 [doi] PST - ppublish SO - J Nanotechnol Mater Sci. 2015 Sep 7;2(2):1-6. doi: 10.15436/2377-1372.15.015.