PMID- 26284419
OWN - NLM
STAT- MEDLINE
DCOM- 20161014
LR  - 20161230
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 32
IP  - 11
DP  - 2015
TI  - Determination and surveillance of hydrocortisone and progesterone in livestock 
      products by liquid chromatography-tandem mass spectrometry.
PG  - 1833-41
LID - 10.1080/19440049.2015.1084053 [doi]
AB  - A simple analytical method for the determination of hydrocortisone and 
      progesterone in bovine, swine, and chicken muscle and eggs was developed. 
      Hydrocortisone and progesterone were extracted with acetonitrile and subsequently 
      cleaned-up using an Oasis HLB mini-cartridge. The method was validated in 
      accordance with Japanese guidelines and exhibited trueness from 86.6% to 104.3% 
      and precision (relative standard deviations (RSDs) of repeatability and within 
      reproducibility were under 8.7% and 11.7%, respectively). The method was applied 
      to 103 bovine muscle, 137 swine muscle, 69 chicken muscle and 52 egg samples that 
      were commercially available in Tokyo, Japan. The hydrocortisone concentration was 
      0.9-41.2 microg kg(-1) in all bovine muscle samples, with an average of 7.7 microg kg(-1) 
      and a median of 6.2 microg kg(-1). The progesterone concentration in 50 samples 
      exceeded the limit of quantification (LOQ) and reached a maximum of 95.4 microg 
      kg(-1). Hydrocortisone was also detected in all swine muscle samples at 
      concentrations of 2.0-56.0 microg kg(-1). Its average and median concentrations 
      amounted to 13.1 and 11.3 microg kg(-1), respectively. Twenty-three samples contained 
      progesterone levels surpassing the LOQ, with a maximum concentration of 107.0 microg 
      kg(-1). No chicken muscle samples contained any of the analytes. The progesterone 
      concentration was 15.5-200.0 microg kg(-1) in all egg samples, with an average of 
      95.4 microg kg(-1) and a median of 90.5 microg kg(-1).
FAU - Nakajima, Takayuki
AU  - Nakajima T
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Tsuruoka, Yumi
AU  - Tsuruoka Y
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Kanda, Maki
AU  - Kanda M
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Hayashi, Hiroshi
AU  - Hayashi H
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Hashimoto, Tsuneo
AU  - Hashimoto T
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Matsushima, Youko
AU  - Matsushima Y
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Yoshikawa, Souichi
AU  - Yoshikawa S
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Nagano, Chieko
AU  - Nagano C
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Okutomi, Yuki
AU  - Okutomi Y
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
FAU - Takano, Ichiro
AU  - Takano I
AD  - a Tokyo Metropolitan Institute of Public Health , Shinjuku-ku , Tokyo 169-0073 , 
      Japan.
LA  - eng
PT  - Journal Article
DEP - 20150918
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Environmental Pollutants)
RN  - 4G7DS2Q64Y (Progesterone)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Animals
MH  - Cattle
MH  - Chickens
MH  - Chromatography, High Pressure Liquid
MH  - Eggs/*analysis
MH  - Environmental Monitoring
MH  - Environmental Pollutants/*analysis
MH  - *Food Analysis
MH  - Hydrocortisone/*analysis
MH  - Japan
MH  - Meat/analysis
MH  - Muscles/*chemistry
MH  - Progesterone/*analysis
MH  - Swine
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - QuEChERS
OT  - liquid chromatography-tandem mass spectrometry
OT  - livestock products
OT  - steroid hormone
OT  - surveillance
EDAT- 2015/08/19 06:00
MHDA- 2016/10/16 06:00
CRDT- 2015/08/19 06:00
PHST- 2015/08/19 06:00 [entrez]
PHST- 2015/08/19 06:00 [pubmed]
PHST- 2016/10/16 06:00 [medline]
AID - 10.1080/19440049.2015.1084053 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(11):1833-41. 
      doi: 10.1080/19440049.2015.1084053. Epub 2015 Sep 18.