PMID- 26291741 OWN - NLM STAT- MEDLINE DCOM- 20170309 LR - 20220311 IS - 1744-5205 (Electronic) IS - 0882-0538 (Linking) VI - 32 IP - 2 DP - 2017 TI - Comparison of Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Pigment Dispersion Syndrome, Pigmentary Glaucoma, and Healthy Subjects with Spectral-domain OCT. PG - 204-209 LID - 10.3109/08820538.2015.1053623 [doi] AB - PURPOSE: To evaluate the ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) thickness in pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) with RTVue spectral domain optical coherence tomography (SD-OCT). METHODS: A total of 102 subjects were enrolled: 29 with PDS, 18 with PG, and 55 normal subjects. Full ophthalmic examination including visual field analysis was performed. SD-OCT was used to analyze GCC superior, GCC inferior, and average RNFL thickness. To compare the discrimination capabilities, the areas under the receiver operating characteristic curves were assessed. RESULTS: Superior GCC, inferior GCC, and RNFL thickness values of patients with PG were statistically signicantly lower than those of patients with PDS (p < 0.001) and healthy individuals (p < 0.001 for all). No statistically significant difference was found between PDS and normal subjects in same parameters (p > 0.05). CONCLUSIONS: The SD-OCT-derived GCC and RNFL thickness parameters can be useful to discriminate PG from both PDS and normal subjects. FAU - Arifoglu, Hasan Basri AU - Arifoglu HB AD - a Kayseri Education and Research Hospital, Department of Ophthalmology , Kayseri , Turkey. FAU - Simavli, Huseyin AU - Simavli H AD - b Pamukkale University, School of Medicine, Department of Ophthalmology , Denizli , Turkey. FAU - Midillioglu, Inci AU - Midillioglu I AD - c Ankara Training and Education Hospital, Ophthalmology Department , Ankara , Turkey. FAU - Berk Ergun, Sule AU - Berk Ergun S AD - d Ankara Ataturk Training and Research Hospital , Ankara , Turkey , and. FAU - Simsek, Saban AU - Simsek S AD - e Maltepe University School of Medicine, Department of Ophthalmology , Istanbul , Turkey. LA - eng PT - Comparative Study PT - Journal Article DEP - 20150820 PL - England TA - Semin Ophthalmol JT - Seminars in ophthalmology JID - 8610759 RN - Glaucoma-Related Pigment Dispersion Syndrome SB - IM MH - Adult MH - Cross-Sectional Studies MH - Female MH - Glaucoma, Open-Angle/*diagnosis MH - Healthy Volunteers MH - Humans MH - Male MH - Middle Aged MH - Nerve Fibers/*pathology MH - Prospective Studies MH - Retinal Ganglion Cells/*pathology MH - Retinal Pigment Epithelium/pathology MH - Tomography, Optical Coherence/*methods OTO - NOTNLM OT - Ganglion cell layer OT - optical coherence tomography OT - pigment dispersion OT - pigmentary glaucoma OT - retinal nerve fiber layer EDAT- 2015/08/21 06:00 MHDA- 2017/03/10 06:00 CRDT- 2015/08/21 06:00 PHST- 2015/08/21 06:00 [pubmed] PHST- 2017/03/10 06:00 [medline] PHST- 2015/08/21 06:00 [entrez] AID - 10.3109/08820538.2015.1053623 [doi] PST - ppublish SO - Semin Ophthalmol. 2017;32(2):204-209. doi: 10.3109/08820538.2015.1053623. Epub 2015 Aug 20.