PMID- 26292405
OWN - NLM
STAT- MEDLINE
DCOM- 20150908
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 33
IP  - 4
DP  - 2015 Apr
TI  - [Determination of 22 acidic dyes in edible packagings by high performance liquid 
      chromatography-tandem mass spectrometry].
PG  - 363-70
AB  - A method for the simultaneous determination of 22 acidic dyes (acid yellow 23, 
      acid red 18, acid blue 7, etc) in edible packagings was developed using high 
      performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The 
      samples were extracted with acetonitrile-methanol (5:5, v/v) , and then cleaned 
      up with Strata-X-AW solid-phase extractor. The analytes were separated on a 
      Zorbax Eclipse Plus C18 column (100 mm x 3.0 mm, 1.8 microm) by gradient elution with 
      acetonitrile-10 mmol/L ammonium acetate as the mobile phases. The 22 acidic dyes 
      were determined by electrospray negative ion source (ESI-), and multiple reaction 
      monitoring (MRM) mode. The qualitative analysis was based on the retention times 
      and characteristic ion pairs consisting of one parent ion and two fragment ions, 
      and the quantitative analysis was carried out by matrix-matched external standard 
      method. The results showed that the calibration curves had good linearity for the 
      22 acidic dyes, and the correlation coefficients (r2) were larger than 0. 991. 
      The limits of quantitation (LOQs, S/N >/= 10) were in the range of 0.1-2.0 mg/kg in 
      three different matrices (plant capsule, gelatine capsule, oblatum). The average 
      recoveries were in the range of 78.4%-109.5% for the 22 acidic dyes with the 
      relative standard deviations (RSDs) from 4.6% to 14.5% at three spiked levels (1 
      x LOQ, 2 x LOQ and 10 x LOQ). This method is suitable for the determination of 
      acidic dyes in edible packagings with the characteristics of high accuracy and 
      precision.
FAU - Su, Youzhi
AU  - Su Y
FAU - Liu, Jun
AU  - Liu J
FAU - Li, Fang
AU  - Li F
FAU - Lei, Hongqin
AU  - Lei H
FAU - Li, Yanmei
AU  - Li Y
FAU - Liu, Xubin
AU  - Liu X
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Coloring Agents)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Coloring Agents/*analysis
MH  - *Food Packaging
MH  - Fruit
MH  - Tandem Mass Spectrometry
EDAT- 2015/08/22 06:00
MHDA- 2015/09/09 06:00
CRDT- 2015/08/22 06:00
PHST- 2015/08/22 06:00 [entrez]
PHST- 2015/08/22 06:00 [pubmed]
PHST- 2015/09/09 06:00 [medline]
AID - 10.3724/sp.j.1123.2014.12009 [doi]
PST - ppublish
SO  - Se Pu. 2015 Apr;33(4):363-70. doi: 10.3724/sp.j.1123.2014.12009.