PMID- 26294363 OWN - NLM STAT- MEDLINE DCOM- 20160516 LR - 20190201 IS - 1757-790X (Electronic) IS - 1757-790X (Linking) VI - 2015 DP - 2015 Aug 20 TI - Hepatic abscess as a paradoxical response to antituberculous chemotherapy for tubercular lymphadenitis. LID - 10.1136/bcr-2015-211936 [doi] LID - bcr2015211936 AB - Tubercular liver abscess developing as a paradoxical reaction (PR) to antitubercular therapy (ATT) is relatively uncommon in the absence of disseminated disease and immunocompromised status of the host even in countries such as India where the disease is rampant. We report a rare case of hepatic abscess that developed paradoxically during antituberculous therapy for tubercular lymphadenitis in a 30-year-old woman who tested negative for HIV. Diagnosis was performed with the help of ultrasonography (USG)-guided aspiration of the abscess followed by cytopathological examination and PCR confirmation of the disease from the USG-guided aspirate. The patient responded well to oral corticosteroid therapy without any alteration of the ongoing ATT regimen. Details of the case and other relevant literature regarding the pathogenesis of this event are discussed in detail. CI - 2015 BMJ Publishing Group Ltd. FAU - Meena, Manoj AU - Meena M AD - Department of Respiratory Medicine, Jawaharlal Nehru Medical College, Ajmer, Rajasthan, India. FAU - Gupta, Neeraj AU - Gupta N AD - Department of Respiratory Medicine, Jawaharlal Nehru Medical College, Ajmer, Rajasthan, India. FAU - Kewlani, Jaiprakash AU - Kewlani J AD - Department of Respiratory Medicine, Jawaharlal Nehru Medical College, Ajmer, Rajasthan, India. FAU - Kumararesan, Sabarigirivasan Harish Vijayadeepan AU - Kumararesan SH AD - Department of Respiratory Medicine, Jawaharlal Nehru Medical College, Ajmer, Rajasthan, India. LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20150820 PL - England TA - BMJ Case Rep JT - BMJ case reports JID - 101526291 RN - 0 (Adrenal Cortex Hormones) RN - 0 (Antitubercular Agents) SB - IM MH - Adrenal Cortex Hormones/*therapeutic use MH - Adult MH - Antitubercular Agents/*adverse effects/therapeutic use MH - Female MH - Humans MH - India MH - Liver/diagnostic imaging/pathology MH - Liver Abscess/chemically induced/*diagnosis MH - Tuberculosis, Hepatic/*drug therapy MH - Tuberculosis, Lymph Node/*complications/drug therapy MH - Ultrasonography PMC - PMC4550924 EDAT- 2015/08/22 06:00 MHDA- 2016/05/18 06:00 PMCR- 2017/08/20 CRDT- 2015/08/22 06:00 PHST- 2015/08/22 06:00 [entrez] PHST- 2015/08/22 06:00 [pubmed] PHST- 2016/05/18 06:00 [medline] PHST- 2017/08/20 00:00 [pmc-release] AID - bcr-2015-211936 [pii] AID - 10.1136/bcr-2015-211936 [doi] PST - epublish SO - BMJ Case Rep. 2015 Aug 20;2015:bcr2015211936. doi: 10.1136/bcr-2015-211936.