PMID- 26302026
OWN - NLM
STAT- MEDLINE
DCOM- 20160629
LR  - 20221207
IS  - 1557-8518 (Electronic)
IS  - 1540-4196 (Linking)
VI  - 13
IP  - 8
DP  - 2015 Oct
TI  - Prevalence of Prediabetes Based on Fasting Plasma Glucose and Glycosylated 
      Hemoglobin in an At-Risk Mexican Population.
PG  - 352-5
LID - 10.1089/met.2015.0040 [doi]
AB  - BACKGROUND: In Latin America, there are no published studies of the prevalence of 
      prediabetes using the glycosylated hemoglobin (HbA1c) criterion in addition to 
      fasting plasma glucose (FPG). Therefore, here we determined the prevalence of 
      prediabetes using FPG and/or HbA1c in a Mexican population at risk for type 2 
      diabetes mellitus (T2DM) and cardiovascular disease. METHODS: This 
      cross-sectional study included 384 primary care users without a known diagnosis 
      of prediabetes or T2DM and with at least one risk factor for T2DM and 
      cardiovascular disease. An FPG 100-125 mg/dL and/or an HbA1c 5.7-6.4% were 
      considered positive for prediabetes. Point prevalence and 95% confidence 
      intervals (CI) were estimated overall and stratified by age, sex, and nutritional 
      status. Mann-Whitney and chi-squared tests were used. P values < 0.05 were 
      considered significant. RESULTS: The prevalence of prediabetes was 74.7% (95% CI, 
      70.2%-78.8%) using FPG or HbA1c criteria for positivity, 60.4% using FPG alone 
      (95% CI, 55.5%-65.3%), 49.8% using HbA1c alone (95% CI, 44.4-55.3%); and 32.9% 
      using FPG and HbA1c (95% CI, 27.8%-38.0%). Prevalence was higher in patients >/=50 
      years old (p < 0.001) and in the overweight-obesity group (p = 0.04) using all 
      criteria except for HbA1c alone. CONCLUSIONS: The prevalence of prediabetes in a 
      Mexican population at risk for cardiovascular disease and/or T2DM was high. 
      Prediabetes is definitely a public health problem. Future studies are needed to 
      examine the effectiveness and efficiency of pragmatic strategies to reverse the 
      status of prediabetes and, therefore, reduce the incidence of T2DM.
FAU - Villanueva-Sosa, Lorena Guadalupe
AU  - Villanueva-Sosa LG
AD  - 1 Unidad de Medicina Familiar No. 31, Instituto Mexicano del Seguro Social , San 
      Nicolas de los Garza, Mexico .
FAU - Cordero-Franco, Hid Felizardo
AU  - Cordero-Franco HF
AD  - 1 Unidad de Medicina Familiar No. 31, Instituto Mexicano del Seguro Social , San 
      Nicolas de los Garza, Mexico .
FAU - Salinas-Martinez, Ana Maria
AU  - Salinas-Martinez AM
AD  - 2 Unidad de Investigacion Epidemiologica y en Servicios de Salud, Instituto 
      Mexicano del Seguro Social , Monterrey, Mexico .
AD  - 3 Universidad Autonoma de Nuevo Leon , Facultad de Salud Publica y Nutricion, 
      Monterrey, Mexico .
LA  - eng
PT  - Journal Article
DEP - 20150824
PL  - United States
TA  - Metab Syndr Relat Disord
JT  - Metabolic syndrome and related disorders
JID - 101150318
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose/*metabolism
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/blood/epidemiology
MH  - Fasting/*blood
MH  - Female
MH  - Glycated Hemoglobin/*analysis
MH  - Humans
MH  - Male
MH  - Mexico/epidemiology
MH  - Middle Aged
MH  - Prediabetic State/*blood/*epidemiology
MH  - Prevalence
MH  - Risk Factors
MH  - Young Adult
EDAT- 2015/08/25 06:00
MHDA- 2016/06/30 06:00
CRDT- 2015/08/25 06:00
PHST- 2015/08/25 06:00 [entrez]
PHST- 2015/08/25 06:00 [pubmed]
PHST- 2016/06/30 06:00 [medline]
AID - 10.1089/met.2015.0040 [doi]
PST - ppublish
SO  - Metab Syndr Relat Disord. 2015 Oct;13(8):352-5. doi: 10.1089/met.2015.0040. Epub 
      2015 Aug 24.