PMID- 26306066 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150826 LR - 20201001 IS - 0971-4502 (Print) IS - 0974-0449 (Electronic) IS - 0971-4502 (Linking) VI - 31 IP - 4 DP - 2015 Dec TI - Allogeneic Hematopoietic Stem Cell Transplantation: A Salvage Treatment for Relapsed or Refractory Lymphoma. PG - 426-33 LID - 10.1007/s12288-014-0497-7 [doi] AB - To analyze the efficacy and safety of allogeneic hematopoietic stem cell transplantation (Allo-HSCT) in patients with relapsed or refractory lymphoma, the therapeutic efficacy, safety, and survival of 23 patients were evaluated. There were 18 (78.3 %) patients with relapsed lymphoma and 5 (21.7 %) patients with refractory lymphoma. Patients were grafted from human leukocyte antigen (HLA)-matched (10) or mismatched (7) related donors, or matched unrelated donors (6). The responses after Allo-HSCT included 13 (56.5 %) cases of complete remission, 5 (21.7 %) cases of partial remission, and 5 (21.7 %) cases of progressive disease. Overall, 16 of 23 patients were alive at a median follow up of 1,035 days (range 60-2,613), five patients died because of non-relapsed mortality, and two patients died of progressive disease. Progression-free survival rates were 64.6 and 48.4 % at 12 and 24 months, respectively, and overall survival rates were 68.6 and 59.5 % at 12 and 24 months, respectively. Allo-HSCT may be a salvage treatment for relapsed or refractory lymphoma. Myeloablative conditioning regimens may be effective and safe. FAU - Wang, Jing-Shi AU - Wang JS AD - Department of Hematology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China. FAU - Wang, Zhao AU - Wang Z AD - Department of Hematology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China. FAU - Wang, Yi-Ni AU - Wang YN AD - Department of Hematology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China. FAU - Wu, Lin AU - Wu L AD - Department of Hematology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China. FAU - Fu, Li AU - Fu L AD - Department of Hematology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China. FAU - Wei, Na AU - Wei N AD - Department of Hematology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China. LA - eng PT - Journal Article DEP - 20150109 PL - India TA - Indian J Hematol Blood Transfus JT - Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion JID - 9425818 PMC - PMC4542769 OTO - NOTNLM OT - Allogeneic hematopoietic stem cell transplantation OT - Lymphoma OT - Refractory OT - Relapse EDAT- 2015/08/26 06:00 MHDA- 2015/08/26 06:01 PMCR- 2016/12/01 CRDT- 2015/08/26 06:00 PHST- 2014/10/12 00:00 [received] PHST- 2014/12/30 00:00 [accepted] PHST- 2015/08/26 06:00 [entrez] PHST- 2015/08/26 06:00 [pubmed] PHST- 2015/08/26 06:01 [medline] PHST- 2016/12/01 00:00 [pmc-release] AID - 497 [pii] AID - 10.1007/s12288-014-0497-7 [doi] PST - ppublish SO - Indian J Hematol Blood Transfus. 2015 Dec;31(4):426-33. doi: 10.1007/s12288-014-0497-7. Epub 2015 Jan 9.