PMID- 26310706 OWN - NLM STAT- MEDLINE DCOM- 20170601 LR - 20190221 IS - 1614-7499 (Electronic) IS - 0944-1344 (Linking) VI - 24 IP - 10 DP - 2017 Apr TI - Detoxification effects of phytonutrients against environmental toxicants and sharing of clinical experience on practical applications. PG - 8946-8956 LID - 10.1007/s11356-015-5263-3 [doi] AB - According to the Food and Health Bureau and Trade and Industry Department of the Hong Kong Government, 90 % of the total food supply in Hong Kong was imported from the Mainland China. In addition, the hidden or illegal use of prohibited pesticides, food adulteration (e.g., using industrial salt in food processing, using gutter oil as cooking oil), and pollutions were periodically reported by the media. Excessive exposure to toxic heavy metals or persistent organic pollutants (POPs) from diet or environmental is inevitable amid industrialization and pollution. Understanding of the detoxification ability among nutrients in plant-based food (i.e., phytonutrients in green tea, onion, garlic, coriander, and turmeric) offers therapeutic and preventive effects against the poisoning effects due to these pollutants. Oxidative stress and pro-inflammatory actions are the common mechanisms for heavy metals or POPs toxicities, while phytonutrients counteracts these cellular insults by anti-oxidation, upregulation of anti-inflammatory pathways, and chelation. FAU - Chung, Raymond Tsz Man AU - Chung RT AD - Mineralysis, 1103 Luk Yu Building, 24-26 Stanley Street, Central, Hong Kong. lab@mineralysis.com.hk. LA - eng PT - Journal Article DEP - 20150828 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 0 (Metals, Heavy) RN - 0 (Phytochemicals) SB - IM MH - China MH - Heavy Metal Poisoning MH - Hong Kong MH - Metals, Heavy/*toxicity MH - *Phytochemicals MH - Poisoning OTO - NOTNLM OT - Anti-inflammation OT - Anti-oxidation OT - Chelation OT - Detoxification OT - Heavy metal poisoning OT - Oxidative stress OT - Persistent organic pollutant OT - Phytonutrients EDAT- 2015/08/28 06:00 MHDA- 2017/06/02 06:00 CRDT- 2015/08/28 06:00 PHST- 2015/03/04 00:00 [received] PHST- 2015/08/17 00:00 [accepted] PHST- 2015/08/28 06:00 [pubmed] PHST- 2017/06/02 06:00 [medline] PHST- 2015/08/28 06:00 [entrez] AID - 10.1007/s11356-015-5263-3 [pii] AID - 10.1007/s11356-015-5263-3 [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2017 Apr;24(10):8946-8956. doi: 10.1007/s11356-015-5263-3. Epub 2015 Aug 28.