PMID- 26317629
OWN - NLM
STAT- MEDLINE
DCOM- 20160524
LR  - 20181113
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 10
IP  - 8
DP  - 2015
TI  - The Effect of Preoperative Oral Carbohydrate or Oral Rehydration Solution on 
      Postoperative Quality of Recovery: A Randomized, Controlled Clinical Trial.
PG  - e0133309
LID - 10.1371/journal.pone.0133309 [doi]
LID - e0133309
AB  - BACKGROUND: Numerous studies have demonstrated the beneficial effects of 
      preoperative administration of oral carbohydrate (CHO) or oral rehydration 
      solution (ORS). However, the effects of preoperative CHO or ORS on postoperative 
      quality of recovery after anesthesia remain unclear. Consequently, the purpose of 
      the current study was to evaluate the effect of preoperative CHO or ORS on 
      patient recovery, using the Quality of Recovery 40 questionnaire (QoR-40). 
      METHODS: This prospective, randomized, controlled clinical trial included 
      American Society of Anesthesiologists (ASA) physical status 1 and 2 adult 
      patients, who were scheduled to undergo a surgical procedure of body surface. 
      Subjects were randomized to one of the three groups: 1) preoperative CHO group, 
      2) preoperative ORS group, and 3) control group. The primary outcome was the 
      global QoR-40 administered 24 h after surgery. Intraoperative use of vasopressor, 
      intraoperative body temperature changes, and postoperative nausea and vomiting 
      (PONV) were also evaluated. RESULTS: We studied 134 subjects. The median 
      [interquartile range (IQR)] global QoR-40 scores 24 h after the surgery were 187 
      [177-197], 186 [171-200], and 184 [171-198] for the CHO, ORS, and control groups, 
      respectively (p = 0.916). No significant differences existed between the groups 
      regarding intraoperative vasopressor use during the surgery (p = 0.475). 
      CONCLUSIONS: Results of the current study indicated that the preoperative 
      administration of either CHO or ORS did not improve the quality of recovery in 
      patients undergoing minimally invasive body surface surgery. TRIAL REGISTRATION: 
      www.umin.ac.jp UMIN000009388 
      https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&recptno=R000011029&language=E.
FAU - Asakura, Ayako
AU  - Asakura A
AD  - Department of Anesthesiology and Critical Care Medicine, Yokohama City University 
      Graduate School of Medicine, Yokohama, Japan.
FAU - Mihara, Takahiro
AU  - Mihara T
AD  - Department of Anesthesiology and Critical Care Medicine, Yokohama City University 
      Graduate School of Medicine, Yokohama, Japan; Department of Anesthesiology, 
      Kanagawa Children's Medical Center, Yokohama, Japan.
FAU - Goto, Takahisa
AU  - Goto T
AD  - Department of Anesthesiology and Critical Care Medicine, Yokohama City University 
      Graduate School of Medicine, Yokohama, Japan.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20150828
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
RN  - 0 (Carbohydrates)
RN  - 0 (Rehydration Solutions)
RN  - 0 (Vasoconstrictor Agents)
SB  - IM
MH  - Administration, Oral
MH  - Adult
MH  - Aged
MH  - Body Temperature/*drug effects
MH  - Carbohydrates/*administration & dosage
MH  - Female
MH  - Humans
MH  - Intraoperative Period
MH  - Male
MH  - Middle Aged
MH  - Postoperative Nausea and Vomiting/*epidemiology/etiology
MH  - Postoperative Period
MH  - Preoperative Care
MH  - Prospective Studies
MH  - Rehydration Solutions/*administration & dosage
MH  - Vasoconstrictor Agents/*therapeutic use
MH  - Young Adult
PMC - PMC4552663
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2015/09/01 06:00
MHDA- 2016/05/25 06:00
PMCR- 2015/08/28
CRDT- 2015/08/29 06:00
PHST- 2015/04/30 00:00 [received]
PHST- 2015/06/25 00:00 [accepted]
PHST- 2015/08/29 06:00 [entrez]
PHST- 2015/09/01 06:00 [pubmed]
PHST- 2016/05/25 06:00 [medline]
PHST- 2015/08/28 00:00 [pmc-release]
AID - PONE-D-15-12116 [pii]
AID - 10.1371/journal.pone.0133309 [doi]
PST - epublish
SO  - PLoS One. 2015 Aug 28;10(8):e0133309. doi: 10.1371/journal.pone.0133309. 
      eCollection 2015.