PMID- 26322189
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150831
LR  - 20200930
IS  - 1949-8462 (Print)
IS  - 1949-8462 (Electronic)
VI  - 7
IP  - 8
DP  - 2015 Aug 26
TI  - Right ventricular septal pacing: Safety and efficacy in a long term follow up.
PG  - 490-8
LID - 10.4330/wjc.v7.i8.490 [doi]
AB  - AIM: To evaluate the safety and efficacy of the permanent high interventricular 
      septal pacing in a long term follow up, as alternative to right ventricular 
      apical pacing. METHODS: We retrospectively evaluated: (1) 244 patients (74 +/- 8 
      years; 169 men, 75 women) implanted with a single (132 pts) or dual chamber (112 
      pts) pacemaker (PM) with ventricular screw-in lead placed at the right 
      ventricular high septal parahisian site (SEPTAL pacing); (2) 22 patients with 
      permanent pacemaker and low percentage of pacing (< 20%) (NO pacing); (3) 33 
      patients with high percentage (> 80%) right ventricular apical pacing (RVA). All 
      patients had a narrow spontaneous QRS (101 +/- 14 ms). We evaluated New York Heart 
      Association (NYHA) class, quality of life (QoL), 6 min walking test (6MWT) and 
      left ventricular function (end-diastolic volume, LV-EDV; end-systolic volume, 
      LV-ESV; ejection fraction, LV-EF) with 2D-echocardiography. RESULTS: Pacing 
      parameters were stable during follow up (21 mo/patient). In SEPTAL pacing group 
      we observed an improvement in NYHA class, QoL score and 6MWT. While LV-EDV didn't 
      significantly increase (104 +/- 40 mL vs 100 +/- 37 mL; P = 0.35), LV-ESV slightly 
      increased (55 +/- 31 mL vs 49 +/- 27 mL; P = 0.05) and LV-EF slightly decreased (49% 
      +/- 11% vs 53% +/- 11%; P = 0.001) but never falling < 45%. In the RVA pacing control 
      group we observed a worsening of NYHA class and an important reduction of LV-EF 
      (from 56% +/- 6% to 43% +/- 9%, P < 0.0001). CONCLUSION: Right ventricular permanent 
      high septal pacing is safe and effective in a long term follow up evaluation; it 
      could be a good alternative to the conventional RVA pacing in order to avoid its 
      deleterious effects.
FAU - Occhetta, Eraldo
AU  - Occhetta E
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Quirino, Gianluca
AU  - Quirino G
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Baduena, Lara
AU  - Baduena L
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Nappo, Rosaria
AU  - Nappo R
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Cavallino, Chiara
AU  - Cavallino C
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Facchini, Emanuela
AU  - Facchini E
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Pistelli, Paolo
AU  - Pistelli P
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Magnani, Andrea
AU  - Magnani A
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Bortnik, Miriam
AU  - Bortnik M
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Francalacci, Gabriella
AU  - Francalacci G
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Dell'Era, Gabriele
AU  - Dell'Era G
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Plebani, Laura
AU  - Plebani L
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
FAU - Marino, Paolo
AU  - Marino P
AD  - Eraldo Occhetta, Rosaria Nappo, Emanuela Facchini, Andrea Magnani, Miriam 
      Bortnik, Gabriella Francalacci, Gabriele Dell'Era, Laura Plebani, Paolo Marino, 
      Cardiology Department, AOU Maggiore della Carita, 28100 Novara, Italy.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Cardiol
JT  - World journal of cardiology
JID - 101537090
PMC - PMC4549783
OTO - NOTNLM
OT  - Left ventricular cardiac function
OT  - Parahisian pacing
OT  - Permanent cardiac pacing
OT  - Resynchronization therapy
OT  - Right ventricular septal pacing
EDAT- 2015/09/01 06:00
MHDA- 2015/09/01 06:01
PMCR- 2015/08/26
CRDT- 2015/09/01 06:00
PHST- 2015/01/25 00:00 [received]
PHST- 2015/06/05 00:00 [revised]
PHST- 2015/06/18 00:00 [accepted]
PHST- 2015/09/01 06:00 [entrez]
PHST- 2015/09/01 06:00 [pubmed]
PHST- 2015/09/01 06:01 [medline]
PHST- 2015/08/26 00:00 [pmc-release]
AID - 10.4330/wjc.v7.i8.490 [doi]
PST - ppublish
SO  - World J Cardiol. 2015 Aug 26;7(8):490-8. doi: 10.4330/wjc.v7.i8.490.