PMID- 26324283
OWN - NLM
STAT- MEDLINE
DCOM- 20160706
LR  - 20220321
IS  - 1432-0932 (Electronic)
IS  - 0940-6719 (Linking)
VI  - 24
IP  - 12
DP  - 2015 Dec
TI  - Assessment of the minimum clinically important difference in neurological 
      function and quality of life after surgery in cervical spondylotic myelopathy 
      patients: a prospective cohort study.
PG  - 2918-23
LID - 10.1007/s00586-015-4208-3 [doi]
AB  - PURPOSE: The purpose of this study was to evaluate the application of the minimum 
      clinically important difference (MCID) concept to postoperative clinical results 
      by using a prospective cohort study in Chinese patients with cervical spondylotic 
      myelopathy (CSM). METHODS: The sample consisted of 113 patients who underwent 
      surgical treatment for CSM in our hospital between February 2008 and November 
      2012. The preoperative and 1-year postoperative modified Japanese Orthopaedic 
      Association (mJOA) scores, mJOA score recovery rate, physical component summary 
      (PCS) and mental component summary (MCS) of the Short Form 36 were collected. The 
      MCID of each outcome measurement was calculated by four approaches including 
      average change, minimum detectable change, change difference and receiver 
      operating characteristic curve. The responsiveness of each measurement was then 
      analyzed. RESULTS: The patients presented a statistically significant improvement 
      (p < 0.01) postoperatively in mJOA, PCS, and MCS. The MCID calculated by four 
      approaches varied from 4.09 to 9.62 for the PCS, 3.11 to 7.41 for the MCS, 1.25 
      to 3.07 for mJOA score, and 31.37 to 44.02% for mJOA recovery rate. In addition, 
      the improvement of the mJOA score owned the highest responsiveness of the four 
      outcome measurements. CONCLUSIONS: The threshold value of the MCID was determined 
      by the choice of the assessment approach. In addition, the recovery rate of the 
      mJOA score appeared to be the most valid and responsive measure of effectiveness 
      of surgery in CSM patients.
FAU - Zhou, Feifei
AU  - Zhou F
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, 
      China.
FAU - Zhang, Yilong
AU  - Zhang Y
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, 
      China.
FAU - Sun, Yu
AU  - Sun Y
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, 
      China. sunyuor@163.com.
FAU - Zhang, Fengshan
AU  - Zhang F
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, 
      China.
FAU - Pan, Shengfa
AU  - Pan S
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, 
      China.
FAU - Liu, Zhongjun
AU  - Liu Z
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20150901
PL  - Germany
TA  - Eur Spine J
JT  - European spine journal : official publication of the European Spine Society, the 
      European Spinal Deformity Society, and the European Section of the Cervical Spine 
      Research Society
JID - 9301980
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cervical Vertebrae/*surgery
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neurodegenerative Diseases/*diagnosis
MH  - Neurologic Examination
MH  - Prospective Studies
MH  - *Quality of Life
MH  - ROC Curve
MH  - Spinal Cord Diseases/physiopathology/psychology/*surgery
MH  - Spondylosis/physiopathology/psychology/*surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Cervical spine
OT  - Cervical spondylotic myelopathy
OT  - Minimum clinically important difference
OT  - Modified Japanese Orthopaedic Association score
OT  - Short Form 36
EDAT- 2015/09/02 06:00
MHDA- 2016/07/07 06:00
CRDT- 2015/09/02 06:00
PHST- 2015/01/29 00:00 [received]
PHST- 2015/08/22 00:00 [accepted]
PHST- 2015/08/22 00:00 [revised]
PHST- 2015/09/02 06:00 [entrez]
PHST- 2015/09/02 06:00 [pubmed]
PHST- 2016/07/07 06:00 [medline]
AID - 10.1007/s00586-015-4208-3 [pii]
AID - 10.1007/s00586-015-4208-3 [doi]
PST - ppublish
SO  - Eur Spine J. 2015 Dec;24(12):2918-23. doi: 10.1007/s00586-015-4208-3. Epub 2015 
      Sep 1.