PMID- 26328927
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20220408
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Linking)
VI  - 26
IP  - 5
DP  - 2016 May
TI  - Hypervascular solid-appearing serous cystic neoplasms of the pancreas: 
      Differential diagnosis with neuroendocrine tumours.
PG  - 1348-58
LID - 10.1007/s00330-015-3961-3 [doi]
AB  - PURPOSE: To describe imaging findings of arterial hypervascular solid-appearing 
      serous cystic neoplasms (SCNs) of the pancreas on CT and MR and determine imaging 
      features differentiating them from neuroendocrine tumours (NETs). MATERIALS AND 
      METHODS: We retrospectively identified 15 arterial hypervascular solid-appearing 
      SCNs and randomly chose 30 size-matched pancreatic NETs. On CT, two radiologists 
      in consensus assessed the size, morphology, and CT attenuation. On MR, 
      predominant signal intensity and the amount of the cystic component on 
      T2-weighted images and ADC maps were evaluated and compared using Fisher's exact 
      and Student's t-test. RESULTS: The mean SCN size was 2.6 cm (range, 0.8-8.3). The 
      CT findings were similar between the two tumours: location, shape, margin, and 
      enhancement pattern. SCNs were significantly more hypodense on non-enhanced CT 
      images than NETs (P = .03). They differed significantly on MR: bright signal 
      intensity (P = .01) and more than a 10% cystic component on T2-weighted images 
      (P = .01) were more common in SCNs than in NETs. All SCNs showed a 
      non-restrictive pattern on the ADC map, while NETs showed diffusion restriction 
      (P < .01). CONCLUSION: Arterial hypervascular solid-appearing SCNs and NETs share 
      similar imaging features. Non-enhanced CT and MR images with T2-weighted images 
      and ADC maps can facilitate the differentiation. KEY POINTS: * Frequency of 
      hypervascular solid-appearing SCNs was 7.3% among surgically confirmed SCNs. * 
      Hypervascular solid-appearing SCN of the pancreas can mimic pancreatic NETs. * 
      Unenhanced CT and MR features help to differentiate the two tumours.
FAU - Park, Hye Sun
AU  - Park HS
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
FAU - Kim, So Yeon
AU  - Kim SY
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea. sykimrad@amc.seoul.kr.
FAU - Hong, Seung-Mo
AU  - Hong SM
AD  - Department of Pathology, University of Ulsan College of Medicine, Asan Medical 
      Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.
FAU - Park, Seong Ho
AU  - Park SH
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
FAU - Lee, Seung Soo
AU  - Lee SS
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
FAU - Byun, Jae Ho
AU  - Byun JH
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
FAU - Kim, Jin Hee
AU  - Kim JH
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
FAU - Kim, Hyoung Jung
AU  - Kim HJ
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
FAU - Lee, Moon-Gyu
AU  - Lee MG
AD  - Department of Radiology and Research Institute of Radiology, University of Ulsan 
      College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, 
      Seoul, 138-736, Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150902
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
SB  - IM
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Image Enhancement/methods
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Neoplasms, Cystic, Mucinous, and Serous/blood supply/*diagnostic imaging
MH  - Neuroendocrine Tumors/*diagnostic imaging
MH  - Pancreas/pathology
MH  - Pancreatic Neoplasms/blood supply/*diagnostic imaging
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - *Tomography, X-Ray Computed
OTO - NOTNLM
OT  - Diagnosis
OT  - Diagnostic imaging
OT  - Magnetic resonance imaging
OT  - Multidetector computed tomography
OT  - Pancreatic neoplasms
EDAT- 2015/09/04 06:00
MHDA- 2016/12/15 06:00
CRDT- 2015/09/03 06:00
PHST- 2015/01/01 00:00 [received]
PHST- 2015/08/03 00:00 [accepted]
PHST- 2015/07/14 00:00 [revised]
PHST- 2015/09/03 06:00 [entrez]
PHST- 2015/09/04 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - 10.1007/s00330-015-3961-3 [pii]
AID - 10.1007/s00330-015-3961-3 [doi]
PST - ppublish
SO  - Eur Radiol. 2016 May;26(5):1348-58. doi: 10.1007/s00330-015-3961-3. Epub 2015 Sep 
      2.