PMID- 26335729
OWN - NLM
STAT- MEDLINE
DCOM- 20160801
LR  - 20151010
IS  - 1525-6049 (Electronic)
IS  - 0886-022X (Linking)
VI  - 37
IP  - 9
DP  - 2015
TI  - Minimally invasive salvage therapy for transplanted renal allografts.
PG  - 1470-5
LID - 10.3109/0886022X.2015.1074492 [doi]
AB  - PURPOSE: To evaluate the effectiveness of interventional therapy for 
      complications of transplanted renal allografts. MATERIALS AND METHODS: Between 
      January 2009 and March 2014, 14 patients underwent interventional therapy for 
      complications of renal allografts. Complications included transplant renal artery 
      stenosis (TRAS), TRAS combined with pseudoaneurysms, transplant renal venous 
      kinking and ureteral obstruction (UO). Serum creatinine (S.Cr) levels were 
      evaluated before and after procedure. The characteristics and procedure outcomes 
      of these patients with vascular and nonvascular complications were also analyzed. 
      RESULTS: All primary procedures were successfully performed, which included 
      percutaneous transluminal angioplasty (PTA) for TRAS (n = 4), stenting and coil 
      embolization for TRAS combined with pseudoaneurysms (n = 1), stenting for renal 
      vein kinking (n = 2), and percutaneous nephrostomy (PCN) for UO (n = 7) and 
      secondary antegrade stent placement in six UO patients after 1 week of PCN. No 
      major procedure related complications occurred. S.Cr level subsequently improved 
      from 6.0 +/- 3.6 to 2.6 +/- 2.1 mg/dL (p < 0.001), as well as patients' clinical 
      features within 1 week after procedure. In our study, the onset time of vascular 
      complications was earlier (<6 months) than nonvascular complications with 
      significant difference (p < 0.001). During follow-up, the patient with TRAS and 
      pseudoaneurysms suffered acute rejection 1 month after treatment and received 
      transplant renal artery embolization. One patient with TRAS showed restenosis 4 
      months after procedure, and was retreated successfully with stenting. Thirteen 
      cases reserved their transplanted renal allografts. CONCLUSION: Interventional 
      therapy could be prior considered for transplanted renal allograft complications 
      as its effectiveness and minimal invasiveness in saving the transplanted renal 
      grafts.
FAU - Liu, Xing-Long
AU  - Liu XL
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Zu, Qing-Quan
AU  - Zu QQ
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Wang, Bin
AU  - Wang B
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Zhou, Chun-Gao
AU  - Zhou CG
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Zhao, Lin-Bo
AU  - Zhao LB
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Xia, Jin-Guo
AU  - Xia JG
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Gu, Min
AU  - Gu M
AD  - b Urology Surgery , The First Affiliated Hospital of Nanjing Medical University , 
      Nanjing , P.R. China.
FAU - Shi, Hai-Bin
AU  - Shi HB
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
FAU - Liu, Sheng
AU  - Liu S
AD  - a Radiology Department , The First Afflicted Hospital of Nanjing Medical 
      University , Nanjing , P.R. China and.
LA  - eng
PT  - Journal Article
DEP - 20150903
PL  - England
TA  - Ren Fail
JT  - Renal failure
JID - 8701128
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aneurysm, False/*surgery
MH  - Angioplasty, Balloon
MH  - Creatinine/blood
MH  - Female
MH  - Humans
MH  - Kidney Transplantation/*adverse effects
MH  - Male
MH  - Middle Aged
MH  - Nephrostomy, Percutaneous/methods
MH  - *Postoperative Complications
MH  - Renal Artery Obstruction/*surgery
MH  - Retrospective Studies
MH  - Salvage Therapy/*methods
MH  - Stents
MH  - Transplantation, Homologous
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - Interventional therapy
OT  - transplant renal artery pseudoaneurysms
OT  - transplant renal artery stenosis
OT  - transplant renal venous kinking
OT  - transplanted renal allograft
EDAT- 2015/09/04 06:00
MHDA- 2016/08/02 06:00
CRDT- 2015/09/04 06:00
PHST- 2015/09/04 06:00 [entrez]
PHST- 2015/09/04 06:00 [pubmed]
PHST- 2016/08/02 06:00 [medline]
AID - 10.3109/0886022X.2015.1074492 [doi]
PST - ppublish
SO  - Ren Fail. 2015;37(9):1470-5. doi: 10.3109/0886022X.2015.1074492. Epub 2015 Sep 3.