PMID- 26339928
OWN - NLM
STAT- MEDLINE
DCOM- 20160601
LR  - 20181202
IS  - 1573-2517 (Electronic)
IS  - 0165-0327 (Linking)
VI  - 187
DP  - 2015 Nov 15
TI  - Functioning in bipolar disorder with substance abuse/dependence in a community 
      sample of young adults.
PG  - 179-82
LID - S0165-0327(15)30567-X [pii]
LID - 10.1016/j.jad.2015.08.046 [doi]
AB  - AIM: To assess the functional impairment of young adults with bipolar disorder 
      with substance abuse/dependence comorbidity. METHOD: Cross-sectional study within 
      a community sample. Bipolar Disorder was assessed by qualified psychologists 
      using The Mini International Neuropsychiatric Interview - PLUS (MINI-PLUS). 
      Substance abuse and dependence was assessed using the "Alcohol, Smoking and 
      Substance Involvement Screening Test" (ASSIST). Functional impairment was 
      assessed using the Functional Assessment Short Test (FAST). RESULTS: The sample 
      included 1259 young adults. The prevalence of Bipolar Disorder (BD) without 
      Substance Abuse/Dependence (SAD) comorbidity was 5.9% (n=74), and the prevalence 
      of bipolar disorder with substance abuse/dependence comorbidity was 1.4% (n=17). 
      Both groups showed higher impairment in overall functioning, interpersonal 
      relationship, and leisure time as compared to controls. In addition, BD+SAD 
      showed higher impairment in the cognitive functioning domain of FAST. LIMITATION: 
      A battery of neuropsychological tests was not performed. CONCLUSION: Functional 
      impairment is associated with BD, independently of substance abuse or dependence. 
      In addition, BD+SAD present a more severe impairment in the cognitive domain of 
      FAST as compared to controls.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Cardoso, Taiane de Azevedo
AU  - Cardoso Tde A
AD  - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e 
      Comportamento, Brazil; University of Texas Health Science Center at Houston - 
      Department of Psychiatry, United States.
FAU - Mondin, Thaise Campos
AU  - Mondin TC
AD  - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e 
      Comportamento, Brazil.
FAU - Souza, Luciano Dias de Mattos
AU  - Souza LD
AD  - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e 
      Comportamento, Brazil.
FAU - da Silva, Ricardo Azevedo
AU  - da Silva RA
AD  - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e 
      Comportamento, Brazil.
FAU - Magalhaes, Pedro V S
AU  - Magalhaes PV
AD  - Laboratorio de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre; 
      Universidade Federal do Rio Grande do Sul - Programa de Pos-Graduacao em Ciencias 
      Medicas: Psiquiatria, Brazil.
FAU - Kapczinski, Flavio
AU  - Kapczinski F
AD  - Laboratorio de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre; 
      Universidade Federal do Rio Grande do Sul - Programa de Pos-Graduacao em Ciencias 
      Medicas: Psiquiatria, Brazil.
FAU - Jansen, Karen
AU  - Jansen K
AD  - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e 
      Comportamento, Brazil; University of Texas Health Science Center at Houston - 
      Department of Psychiatry, United States. Electronic address: 
      karen.jansen@pq.cnpq.br.
LA  - eng
PT  - Journal Article
DEP - 20150828
PL  - Netherlands
TA  - J Affect Disord
JT  - Journal of affective disorders
JID - 7906073
SB  - IM
MH  - Adult
MH  - Bipolar Disorder/*epidemiology/*psychology
MH  - Brazil/epidemiology
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Male
MH  - Prevalence
MH  - Social Behavior
MH  - Substance-Related Disorders/*epidemiology/*psychology
MH  - Young Adult
OTO - NOTNLM
OT  - Bipolar disorder
OT  - Comorbidity
OT  - Functional impairment
OT  - Illicit substance abuse/dependence
OT  - Young adult
EDAT- 2015/09/05 06:00
MHDA- 2016/06/02 06:00
CRDT- 2015/09/05 06:00
PHST- 2015/07/10 00:00 [received]
PHST- 2015/08/20 00:00 [revised]
PHST- 2015/08/21 00:00 [accepted]
PHST- 2015/09/05 06:00 [entrez]
PHST- 2015/09/05 06:00 [pubmed]
PHST- 2016/06/02 06:00 [medline]
AID - S0165-0327(15)30567-X [pii]
AID - 10.1016/j.jad.2015.08.046 [doi]
PST - ppublish
SO  - J Affect Disord. 2015 Nov 15;187:179-82. doi: 10.1016/j.jad.2015.08.046. Epub 
      2015 Aug 28.