PMID- 26344469 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150908 LR - 20200930 IS - 2076-393X (Print) IS - 2076-393X (Electronic) IS - 2076-393X (Linking) VI - 2 IP - 1 DP - 2014 Feb 13 TI - Meningitis in a School-Aged Child due to Haemophilus influenzae Type E during the Post-Conjugate Vaccine Era-Monroe County, NY, 2011. PG - 107-11 LID - 10.3390/vaccines2010107 [doi] AB - In late October 2011, the Monroe County Department of Public Health (MCDPH) was notified of a suspected case of meningitis in a 9-year old girl from Monroe County, NY. Laboratory testing at the New York State Department of Health (NYSDOH) Wadsworth Center confirmed the identification of Haemophilus influenzae serotype e (Hie) isolated from the patient's cerebrospinal fluid (CSF) using real-time polymerase chain reaction (RT-PCR). The universal immunization of infants with conjugate H. influenzae type b (Hib) vaccine has significantly reduced the incidence of invasive Hib disease, including meningitis, one of the most serious complications for infected children. Not surprisingly, as the epidemiology of invasive H. influenzae continues to change, non-Hib serotypes will likely become more common. The findings reported here underscore the importance for clinicians, public health officials, and laboratory staff to consider non-Hib pathogens in pediatric cases of meningitis, especially when initial investigations are inconclusive. FAU - Kennedy, Byron S AU - Kennedy BS AD - Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA. bkennedy@monroecounty.gov. FAU - Weimer, Anita C AU - Weimer AC AD - Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA. acweimer@monroecounty.gov. FAU - Bedard, Brenden AU - Bedard B AD - Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA. bbedard@monroecounty.gov. FAU - Nayak, Jennifer L AU - Nayak JL AD - Department of Pediatrics, University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 690, Rochester, NY 14620, USA. jennifer_nayak@urmc.rochester.edu. FAU - Sacheli, Drew AU - Sacheli D AD - Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA. dsacheli@monroecounty.gov. FAU - Ricci, John AU - Ricci J AD - Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA. jricci@monroecounty.gov. FAU - Meyer, Donna D AU - Meyer DD AD - Mendon Pediatrics, 30 Assembly Drive, Suite 101 PO Box 488 Mendon, NY 14506, USA. drmeyer@mendonpediatrics.com. FAU - Hubbard, Donna AU - Hubbard D AD - Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA. dhubbard@monreocounty.gov. LA - eng PT - Journal Article DEP - 20140213 PL - Switzerland TA - Vaccines (Basel) JT - Vaccines JID - 101629355 PMC - PMC4494195 OTO - NOTNLM OT - Haemophilus influenza OT - public health OT - real-time polymerase chain reaction (RT-PCR) EDAT- 2014/01/01 00:00 MHDA- 2014/01/01 00:01 PMCR- 2014/02/13 CRDT- 2015/09/08 06:00 PHST- 2013/11/22 00:00 [received] PHST- 2014/01/30 00:00 [revised] PHST- 2014/02/10 00:00 [accepted] PHST- 2015/09/08 06:00 [entrez] PHST- 2014/01/01 00:00 [pubmed] PHST- 2014/01/01 00:01 [medline] PHST- 2014/02/13 00:00 [pmc-release] AID - vaccines2010107 [pii] AID - vaccines-02-00107 [pii] AID - 10.3390/vaccines2010107 [doi] PST - epublish SO - Vaccines (Basel). 2014 Feb 13;2(1):107-11. doi: 10.3390/vaccines2010107.