PMID- 26346399 OWN - NLM STAT- MEDLINE DCOM- 20160926 LR - 20181202 IS - 1880-2206 (Electronic) IS - 1347-3182 (Linking) VI - 15 IP - 1 DP - 2016 TI - Contrast-enhanced Steady-state Free Precession in the Assessment of Hypertrophic Obstructive Cardiomyopathy after Alcohol Septal Ablation. PG - 130-6 LID - 10.2463/mrms.2015-0037 [doi] AB - PURPOSE: We evaluated the feasibility of contrast-enhanced steady-state free precession (ceSSFP) in the assessment of myocardial injury and obstruction of the left ventricular outflow tract (LVOT) in patients with hypertrophic obstructive cardiomyopathy (HOCM) after alcohol septal ablation (ASA). METHODS: Twelve patients with HOCM underwent 16 magnetic resonance (MR) examinations following ASA. Precontrast SSFP, ceSSFP and late gadolinium enhancement (LGE) imaging were performed with a 1.5-tesla imager. ceSSFP was performed 3 to 7 min after gadolinium injection. We visually and quantitatively evaluated the signal patterns of the myocardium after ASA on SSFP and LGE MR imaging. We observed the LVOT using ceSSFP in the 3-chamber view. RESULTS: We could visualize ASA-induced myocardial infarction (MI) in all 16 studies by LGE and ceSSFP but in only 6 studies (37.5%) by precontrast SSFP. Contrast was higher between MI and remote myocardium with LGE than ceSSFP (P < 0.01). ASA-induced hypointense regions were well visualized by the 2 sequences after contrast in the 7 patients who underwent MR imaging within 7 weeks of ASA and in a few patients after 80 weeks from ASA. The ceSSFP allowed comparable visualization of the jet flow crossing the LVOT to that derived from echocardiographic data. CONCLUSION: Contrast-enhanced steady-state free precession allows assessment of myocardial injury as well as of the left ventricular outflow tract after alcohol septal ablation in a single scan without penalty in scan time and cine imaging contrast. FAU - Amano, Yasuo AU - Amano Y AD - Department of Radiology, Nippon Medical School. FAU - Yamada, Fumi AU - Yamada F FAU - Kitamura, Mitsunobu AU - Kitamura M FAU - Tachi, Masaki AU - Tachi M FAU - Mine, Kumiko AU - Mine K FAU - Kumita, Shinichiro AU - Kumita S FAU - Takayama, Morimasa AU - Takayama M LA - eng PT - Comparative Study PT - Journal Article DEP - 20150904 PL - Japan TA - Magn Reson Med Sci JT - Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine JID - 101153368 RN - 0 (Contrast Media) RN - 3K9958V90M (Ethanol) RN - AU0V1LM3JT (Gadolinium) SB - IM MH - Ablation Techniques/*methods MH - Aged MH - Aged, 80 and over MH - Cardiomyopathy, Hypertrophic/*surgery MH - *Contrast Media MH - Ethanol/*therapeutic use MH - Feasibility Studies MH - Female MH - *Gadolinium MH - Heart Septum/surgery MH - Heart Ventricles MH - Humans MH - Image Enhancement/*methods MH - Image Processing, Computer-Assisted/methods MH - Magnetic Resonance Imaging, Cine/*methods MH - Male MH - Middle Aged MH - Myocardial Infarction/diagnosis MH - Postoperative Complications/diagnosis MH - Retrospective Studies MH - Ventricular Function, Left/physiology MH - Ventricular Outflow Obstruction/diagnosis EDAT- 2015/09/09 06:00 MHDA- 2016/09/27 06:00 CRDT- 2015/09/09 06:00 PHST- 2015/09/09 06:00 [entrez] PHST- 2015/09/09 06:00 [pubmed] PHST- 2016/09/27 06:00 [medline] AID - 10.2463/mrms.2015-0037 [doi] PST - ppublish SO - Magn Reson Med Sci. 2016;15(1):130-6. doi: 10.2463/mrms.2015-0037. Epub 2015 Sep 4.