PMID- 26357893
OWN - NLM
STAT- MEDLINE
DCOM- 20160711
LR  - 20181202
IS  - 1532-4109 (Electronic)
IS  - 0360-1234 (Linking)
VI  - 50
IP  - 11
DP  - 2015
TI  - Studies on the drug resistance profile of Enterococcus faecium distributed from 
      poultry retailers to hospitals.
PG  - 827-32
LID - 10.1080/03601234.2015.1058106 [doi]
AB  - The multidrug resistant Enterococcus faecium (MEF) strains originating from farm 
      animals are proliferating at a substantial pace to impact downstream food chains 
      and could reach hospitals. This study was conducted to elucidate the drug 
      susceptibility profile of MEF strains collected from poultry products in Ann 
      Arbor, MI area and clinical settings from Michigan State Lab and Moffitt Cancer 
      Center (MCC) in Florida. Presumptive positive Enterococcus isolates at species 
      level were identified by Matrix Assisted Laser Desorption/Ionization 
      Time-of-Flight (MALDI-TOF) analysis. The antibiotic susceptibility profile for 
      both poultry and clinical strains was determined by the Thermo Scientific's 
      Sensititre conform to the National Committee for Clinical Laboratory Standards 
      (NCCLS) and validated via quantitative real-time PCR (qPCR) methods. Out of 50 
      poultry samples (Turkey: n = 30; Chicken: n = 20), 36 samples were positive for 
      Enterococcus species from which 20.83% were identified as E. faecium. All the E. 
      faecium isolates were multidrug resistant and displayed resistance to the last 
      alternative drug, quinupristin/dalfopristin (QD) used to treat vancomycin 
      resistant E. faecium (VRE) in hospitals. Results indicate the presence of MEF 
      strains in food animals and clinical settings that are also resistant to QD.
FAU - Limayem, Alya
AU  - Limayem A
AD  - a Department of Cell Biology, Microbiology and Molecular Biology, University of 
      South Florida , Tampa , Florida , USA.
FAU - Donofrio, Robert Scott
AU  - Donofrio RS
AD  - b Applied Research Center, National Sanitary Foundation , Ann Arbor , Michigan , 
      USA.
FAU - Zhang, Chao
AU  - Zhang C
AD  - a Department of Cell Biology, Microbiology and Molecular Biology, University of 
      South Florida , Tampa , Florida , USA.
FAU - Haller, Edward
AU  - Haller E
AD  - c Department of Integrative Biology, University of South Florida , Tampa , 
      Florida , USA.
FAU - Johnson, Michael G
AU  - Johnson MG
AD  - d Department of Food Science and Center for Food Safety, Institute of Food 
      Science & Engineering, University of Arkansas , Fayetteville , Arkansas , USA.
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Environ Sci Health B
JT  - Journal of environmental science and health. Part. B, Pesticides, food 
      contaminants, and agricultural wastes
JID - 7607167
RN  - 0 (Anti-Bacterial Agents)
RN  - 11006-76-1 (Virginiamycin)
RN  - 126602-89-9 (quinupristin-dalfopristin)
SB  - IM
MH  - Animals
MH  - Anti-Bacterial Agents/pharmacology
MH  - Chickens/microbiology
MH  - Drug Resistance
MH  - *Drug Resistance, Multiple, Bacterial/genetics
MH  - Enterococcus faecium/*drug effects/genetics/isolation & purification
MH  - Hospitals
MH  - Humans
MH  - Michigan
MH  - Microbial Sensitivity Tests
MH  - Poultry/*microbiology
MH  - Real-Time Polymerase Chain Reaction
MH  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
MH  - Turkeys/microbiology
MH  - Virginiamycin/pharmacology
OTO - NOTNLM
OT  - Multidrug resistant E. faecium
OT  - antimicrobial susceptibility profile
OT  - hospitals
OT  - poultry
OT  - virginiamycin
EDAT- 2015/09/12 06:00
MHDA- 2016/07/12 06:00
CRDT- 2015/09/12 06:00
PHST- 2015/09/12 06:00 [entrez]
PHST- 2015/09/12 06:00 [pubmed]
PHST- 2016/07/12 06:00 [medline]
AID - 10.1080/03601234.2015.1058106 [doi]
PST - ppublish
SO  - J Environ Sci Health B. 2015;50(11):827-32. doi: 10.1080/03601234.2015.1058106.