PMID- 26359057
OWN - NLM
STAT- MEDLINE
DCOM- 20151123
LR  - 20150911
IS  - 0529-5815 (Print)
IS  - 0529-5815 (Linking)
VI  - 53
IP  - 6
DP  - 2015 Jun 1
TI  - [Results and predictors of long-term outcomes of off-pump coronary artery bypass 
      grafting: 2 831 cases from a single center].
PG  - 436-41
AB  - OBJECTIVE: To describe the long-term survival of off-pump coronary artery bypass 
      grafting (CABG) and to analysis the risk factors of operative mortality and 
      long-term survival. METHODS: From January 2001 to December 2012, 2 831 patients 
      undergoing off-pump CABG in Peking University People's Hospital, 2 099 cases 
      (74.1%) of them were male, the average age was (63+/-9) years. The perioperative 
      data was retrospectively collected. Binary Logistic regression was used to find 
      the risk factors which affect the operative mortality. Follow-up evaluation was 
      completed regularly. Kaplan-Meier survival curve, Log-rank test and Cox 
      regression model were used to find out factors which affect the long-term result. 
      RESULTS: Totally 2 831 patients underwent isolating off-pump CABG, in whom 45 
      patients died perioperative, 2 786 patients discharged successfully. Binary 
      Logistic regression showed that sex (female) (chi2=4.4, OR=2.307, P=0.035), 
      peripheral vascular disease (chi2=17.4, OR=6.616, P=0.000), New York Heart 
      Association (NYHA) class grade>/=3 (chi2=10.5, OR=3.491, P=0.001), ejection 
      fraction</=40% (chi2=16.9, OR=5.230, P=0.000), emergency surgery (chi2=11.9, OR=5.127, 
      P=0.001) are risk factors of operative mortality. The follow-up time was (74+/-44) 
      months. Totally 107 patients were lost from follow-up, 109 patients died in 
      follow-up. The survival rate at 1, 3, 5 , 8 and 10 years was 97.2%, 95.5%, 94.3%, 
      93.6%, 92.1%, respectively. Univariate analysis showed that age (>65 years), 
      hypertension, renal insufficiency, peripheral vascular disease, history of 
      myocardial infarction, NYHA class grade>/=3 and emergency surgery were risk factors 
      of the long-term survival (chi2=8.150 to 88.241, P<0.05). Cox regression analysis 
      showed that age (>65 years) (chi2=12.1, RR=2.295, P=0.000), renal insufficiency 
      (chi2=12.3, RR=3.160, P=0.000), peripheral vascular disease (chi2=42.5, RR=5.626, 
      P=0.000), NYHA class grade>/=3 (chi2=9.1, RR=1.994, P=0.002) and emergency surgery 
      (chi2=5.5, RR=2.247, P=0.019) were independent risk factors that affect the 
      long-term survival. CONCLUSIONS: Sex (female), peripheral vascular disease, NYHA 
      class grade>/=3, ejection fraction</=40%, emergency surgery are risk factors of 
      operative mortality. Age (>65 years), renal insufficiency, peripheral vascular 
      disease, NYHA class grade>/=3 and emergency surgery are independent risk factors 
      that affect the long-term survival. Off-pump CABG has favorable perioperative and 
      long-term outcome, and it definitely is a very safe and effective technique for 
      coronary artery revascularization.
FAU - Liu, Xi
AU  - Liu X
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Chen, Yu
AU  - Chen Y
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China; Email: chenyu@pkuph.edu.cn.
FAU - Zhao, Zhou
AU  - Zhao Z
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Dong, Suixin
AU  - Dong S
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Liu, Gang
AU  - Liu G
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Chen, Shenglong
AU  - Chen S
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Ling, Yunpeng
AU  - Ling Y
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Li, Hui
AU  - Li H
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Lian, Bo
AU  - Lian B
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Bao, Liming
AU  - Bao L
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
FAU - Yang, Wei
AU  - Yang W
AD  - Department of Cardiovascular Surgery, Peking University People's Hospital, 
      Beijing 100044, China.
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Wai Ke Za Zhi
JT  - Zhonghua wai ke za zhi [Chinese journal of surgery]
JID - 0153611
SB  - IM
MH  - Aged
MH  - Cardiovascular Diseases
MH  - Coronary Artery Bypass, Off-Pump/*mortality
MH  - Coronary Artery Disease/*surgery
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction
MH  - Peripheral Vascular Diseases
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
EDAT- 2015/09/12 06:00
MHDA- 2015/12/15 06:00
CRDT- 2015/09/12 06:00
PHST- 2015/09/12 06:00 [entrez]
PHST- 2015/09/12 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
PST - ppublish
SO  - Zhonghua Wai Ke Za Zhi. 2015 Jun 1;53(6):436-41.