PMID- 26361660
OWN - NLM
STAT- MEDLINE
DCOM- 20160520
LR  - 20181202
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 47
IP  - 7
DP  - 2015 Sep
TI  - Effect of Donor- and Recipient-Related Factors on Arterial Resistance Index After 
      Kidney Transplant.
PG  - 2130-4
LID - S0041-1345(15)00633-8 [pii]
LID - 10.1016/j.transproceed.2015.04.104 [doi]
AB  - BACKGROUND: The assessment of color Doppler resistance index (RI) of the 
      intra-renal arteries has been shown to be a good predictor of short-term and 
      long-term graft survival after kidney transplant. In this study, we investigated 
      the influence of donor- and recipient-related factors on RI evaluated early after 
      kidney transplant. METHODS: We prospectively analyzed 90 kidney transplant 
      patients who underwent RI assessment within the first month after the transplant, 
      subdivided into 2 groups according their RI values lower (group A) or higher 
      (group B) than 0.646 (median value). RESULTS: Patients in group A had a lower 
      human leukocyte antigen (HLA) mismatch number (3.3 +/- 1 versus 3.9 +/- 0.9, P = 
      .007) and were significantly younger (42.8 +/- 11 years versus 47.8 +/- 11 years, P = 
      .03) than patients in group B. All the others variables examined were not 
      significantly different between the 2 groups. Multivariate logistic regression 
      analysis confirmed that HLA mismatch number (P = .03) and recipient age (P = .03) 
      are independent predictors of RI. CONCLUSIONS: Our data suggest that HLA 
      mismatches and donor age can influence recipient kidney vascular resistance in 
      the early period after transplantation.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Saracino, A
AU  - Saracino A
AD  - Basilicata Referral Centre for Transplantation, Hospital of Matera, Matera, 
      Italy. Electronic address: asaracino@inwind.it.
FAU - Santarsia, G
AU  - Santarsia G
AD  - Basilicata Referral Centre for Transplantation, Hospital of Matera, Matera, 
      Italy.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Arteries/*immunology
MH  - Female
MH  - Graft Survival/*immunology
MH  - HLA Antigens/immunology
MH  - Humans
MH  - Kidney/*blood supply
MH  - *Kidney Transplantation
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Prospective Studies
MH  - Tissue Donors
MH  - Vascular Resistance/*immunology
EDAT- 2015/09/13 06:00
MHDA- 2016/05/21 06:00
CRDT- 2015/09/13 06:00
PHST- 2014/12/17 00:00 [received]
PHST- 2015/03/13 00:00 [revised]
PHST- 2015/04/15 00:00 [accepted]
PHST- 2015/09/13 06:00 [entrez]
PHST- 2015/09/13 06:00 [pubmed]
PHST- 2016/05/21 06:00 [medline]
AID - S0041-1345(15)00633-8 [pii]
AID - 10.1016/j.transproceed.2015.04.104 [doi]
PST - ppublish
SO  - Transplant Proc. 2015 Sep;47(7):2130-4. doi: 10.1016/j.transproceed.2015.04.104.