PMID- 26365943
OWN - NLM
STAT- MEDLINE
DCOM- 20170317
LR  - 20220311
IS  - 1897-4279 (Electronic)
IS  - 0022-9032 (Linking)
VI  - 74
IP  - 3
DP  - 2016
TI  - Clinical characteristics and predictors of one-year outcome of heart failure 
      patients with atrial fibrillation compared to heart failure patients in sinus 
      rhythm.
PG  - 251-61
LID - 10.5603/KP.a2015.0180 [doi]
AB  - BACKGROUND: Atrial fibrillation (AF) frequently coexists with heart failure (HF). 
      AIM: To assess clinical characteristics and to identify predictors of one-year 
      outcome of patients hospitalised for HF, depending on whether they were in sinus 
      rhythm (SR) or had AF. METHODS: The study included Polish patients hospitalised 
      for HF, participating in the Heart Failure Pilot Survey of the European Society 
      of Cardiology, who were followed for 12 months after discharge. Patients with 
      paced heart rhythm were excluded from the study. The primary endpoint was 
      all-cause death at 12 months. RESULTS: The final analysis included 587 patients. 
      AF occurred in 215 (36.6%) patients. Compared to patients in SR, patients with AF 
      were older, more often had a history of previous HF hospitalisation, were 
      characterised by a higher New York Heart Association (NYHA) class, higher heart 
      rate, and lower diastolic blood pressure at hospital admission, and had higher 
      serum creatinine and lower haemoglobin concentration at admission. In-hospital 
      mortality was higher in AF patients compared to SR patients (5.1% vs. 2.4%, 
      respectively), but the difference did not reach statistical significance (p = 
      0.1). The primary endpoint occurred in 41 of 215 AF patients (19.1%) and in 40 of 
      372 SR patients (10.8%; p = 0.006). In a multivariate analysis, predictors of the 
      primary endpoint in AF patients were: higher NYHA class at hospital admission (p 
      = 0.02), higher admission heart rate (p = 0.04), lower admission serum sodium 
      concentration (p = 0.0001), and higher heart rate at discharge (p = 0.01). In 
      patients with SR, independent predictors of the primary endpoint included: older 
      age (p = 0.007), lower serum sodium concentration at admission (p = 0.0006), and 
      higher heart rate at discharge (p = 0.008). CONCLUSIONS: Patients with HF and 
      concomitant AF differ significantly from HF patients in SR. In the studied group 
      of real-world HF patients, serum sodium concentration at hospital admission and 
      heart rate at hospital discharge were independent prognostic factors in patients 
      with AF and in patients in SR. In contrast to SR patients, heart rate at hospital 
      admission in AF patients was also predictive of long-term mortality.
FAU - Ozieranski, Krzysztof
AU  - Ozieranski K
FAU - Kaplon-Cieslicka, Agnieszka
AU  - Kaplon-Cieslicka A
AD  - I Katedra i Klinika Kardiologii Warszawskiego Uniwersytetu Medycznego. 
      agnieszka.kaplon@gmail.com.
FAU - Peller, Michal
AU  - Peller M
FAU - Tyminska, Agata
AU  - Tyminska A
FAU - Balsam, Pawel
AU  - Balsam P
FAU - Galas, Michalina
AU  - Galas M
FAU - Marchel, Michal
AU  - Marchel M
FAU - Crespo-Leiro, Marisa
AU  - Crespo-Leiro M
FAU - Maggioni, Aldo Pietro
AU  - Maggioni AP
FAU - Drozdz, Jaroslaw
AU  - Drozdz J
FAU - Opolski, Grzegorz
AU  - Opolski G
LA  - eng
PT  - Journal Article
DEP - 20150914
PL  - Poland
TA  - Kardiol Pol
JT  - Kardiologia polska
JID - 0376352
RN  - 9NEZ333N27 (Sodium)
SB  - IM
MH  - Aged
MH  - Atrial Fibrillation/blood/*complications/diagnosis/physiopathology
MH  - Female
MH  - Heart Failure/blood/*complications/diagnosis/physiopathology
MH  - Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pilot Projects
MH  - Poland
MH  - Prognosis
MH  - Sodium/blood
OTO - NOTNLM
OT  - atrial fibrillation
OT  - heart failure
OT  - hospitalisation
OT  - prognosis
OT  - sinus rhythm
EDAT- 2015/09/15 06:00
MHDA- 2017/03/18 06:00
CRDT- 2015/09/15 06:00
PHST- 2015/05/27 00:00 [received]
PHST- 2015/08/20 00:00 [accepted]
PHST- 2015/07/19 00:00 [revised]
PHST- 2015/09/15 06:00 [entrez]
PHST- 2015/09/15 06:00 [pubmed]
PHST- 2017/03/18 06:00 [medline]
AID - VM/OJS/KP/9873 [pii]
AID - 10.5603/KP.a2015.0180 [doi]
PST - ppublish
SO  - Kardiol Pol. 2016;74(3):251-61. doi: 10.5603/KP.a2015.0180. Epub 2015 Sep 14.