PMID- 26373614
OWN - NLM
STAT- MEDLINE
DCOM- 20171023
LR  - 20190816
IS  - 1475-097X (Electronic)
IS  - 1475-0961 (Linking)
VI  - 37
IP  - 3
DP  - 2017 May
TI  - Body composition, maximal aerobic performance and inflammatory biomarkers in 
      endurance-trained athletes.
PG  - 288-292
LID - 10.1111/cpf.12299 [doi]
AB  - This study was designed to examine the relationships between body composition, 
      cardiorespiratory fitness and simultaneously measured inflammatory parameters in 
      endurance-trained athletes. In 20 well-trained rowers (19.0 +/- 2.9 years; 
      185.6 +/- 4.8 cm; 85.7 +/- 10.8 kg; 17.1 +/- 5.1% body fat; maximal oxygen consumption 
      [VO(2) max]: 63.9 +/- 8.5 ml min(-1)  kg(-1) ), body composition was measured by 
      dual-energy X-ray absorptiometry and cardiorespiratory fitness by direct VO(2) 
      max test. Twelve inflammatory factors [interleukin (IL)-2, IL-4, IL-6, IL-8, 
      IL-10, vascular endothelial growth factor, interferon-gamma (IFN-gamma), tumour 
      necrosis factor-alpha, IL-1alpha, IL-1beta, monocyte chemoattractant protein-1 (MCP-1), 
      epidermal growth factor (EGF)] were analysed from serum samples. Serum IFN-gamma was 
      related (P<0.05) to fat-free mass (FFM) (r = -0.56) and muscle mass (r = -0.50). 
      The stepwise regression analysis showed that IFN-gamma explained 27.5%, and IFN-gamma and 
      IL-6 together explained 39.8% of the variability of FFM, while IFN-gamma explained 
      21.1%, and IFN-gamma together with EGF explained 36.6% of the variability of muscle 
      mass in male rowers. Serum IL-8 (r = -0.65) and VEGF (r = -0.48) correlated 
      (P<0.05) with VO(2) max kg(-1) . Serum IL-8 explained 38.5% of the variability of 
      VO(2) max kg(-1) . Significant correlations were also found among several 
      inflammatory parameters, indicating that various inflammatory cytokines act on 
      the body as an ensemble. In conclusion, this cross-sectional study in 
      endurance-trained male rowers showed that FFM and muscle mass were negatively 
      correlated with serum IFN-gamma level, whereas cardiorespiratory fitness was 
      negatively related to serum IL-8 level.
CI  - (c) 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. 
      Published by John Wiley & Sons Ltd.
FAU - Jurimae, Jaak
AU  - Jurimae J
AD  - Institute of Sport Pedagogy and Coaching Sciences, Centre of Behavioral, Social 
      and Health Sciences, University of Tartu, Tartu, Estonia.
FAU - Tillmann, Vallo
AU  - Tillmann V
AD  - Department of Paediatrics, Children's Clinic of Tartu University Hospital, 
      University of Tartu, Tartu, Estonia.
FAU - Purge, Priit
AU  - Purge P
AD  - Institute of Sport Pedagogy and Coaching Sciences, Centre of Behavioral, Social 
      and Health Sciences, University of Tartu, Tartu, Estonia.
FAU - Jurimae, Toivo
AU  - Jurimae T
AD  - Institute of Sport Pedagogy and Coaching Sciences, Centre of Behavioral, Social 
      and Health Sciences, University of Tartu, Tartu, Estonia.
LA  - eng
PT  - Journal Article
DEP - 20150916
PL  - England
TA  - Clin Physiol Funct Imaging
JT  - Clinical physiology and functional imaging
JID - 101137604
RN  - 0 (Biomarkers)
RN  - 0 (CXCL8 protein, human)
RN  - 0 (IFNG protein, human)
RN  - 0 (Inflammation Mediators)
RN  - 0 (Interleukin-8)
RN  - 82115-62-6 (Interferon-gamma)
SB  - IM
MH  - Absorptiometry, Photon
MH  - Adiposity
MH  - Adolescent
MH  - *Athletes
MH  - Biomarkers/blood
MH  - *Body Composition
MH  - Cross-Sectional Studies
MH  - Exercise Test
MH  - *Exercise Tolerance
MH  - Humans
MH  - Inflammation Mediators/*blood
MH  - Interferon-gamma/blood
MH  - Interleukin-8/blood
MH  - Male
MH  - Oxygen Consumption
MH  - *Physical Endurance
MH  - Physical Fitness
MH  - Young Adult
OTO - NOTNLM
OT  - body composition
OT  - inflammatory profile
OT  - maximal aerobic performance
OT  - rowers
EDAT- 2015/09/17 06:00
MHDA- 2017/10/24 06:00
CRDT- 2015/09/17 06:00
PHST- 2015/05/05 00:00 [received]
PHST- 2015/08/03 00:00 [accepted]
PHST- 2015/09/17 06:00 [pubmed]
PHST- 2017/10/24 06:00 [medline]
PHST- 2015/09/17 06:00 [entrez]
AID - 10.1111/cpf.12299 [doi]
PST - ppublish
SO  - Clin Physiol Funct Imaging. 2017 May;37(3):288-292. doi: 10.1111/cpf.12299. Epub 
      2015 Sep 16.