PMID- 26373760 OWN - NLM STAT- MEDLINE DCOM- 20170227 LR - 20200330 IS - 1432-1084 (Electronic) IS - 0938-7994 (Linking) VI - 26 IP - 6 DP - 2016 Jun TI - Late gadolinium enhancement cardiac imaging on a 3T scanner with parallel RF transmission technique: prospective comparison of 3D-PSIR and 3D-IR. PG - 1547-55 LID - 10.1007/s00330-015-4002-y [doi] AB - OBJECTIVE: To qualitatively and quantitatively compare different late gadolinium enhancement (LGE) sequences acquired at 3T with a parallel RF transmission technique. METHODS: One hundred and sixty participants prospectively enrolled underwent a 3T cardiac MRI with 3 different LGE sequences: 3D Phase-Sensitive Inversion-Recovery (3D-PSIR) acquired 5 minutes after injection, 3D Inversion-Recovery (3D-IR) at 9 minutes and 3D-PSIR at 13 minutes. All LGE-positive patients were qualitatively evaluated both independently and blindly by two radiologists using a 4-level scale, and quantitatively assessed with measurement of contrast-to-noise ratio and LGE maximal surface. Statistical analyses were calculated under a Bayesian paradigm using MCMC methods. RESULTS: Fifty patients (70 % men, 56yo +/- 19) exhibited LGE (62 % were post-ischemic, 30 % related to cardiomyopathy and 8 % post-myocarditis). Early and late 3D-PSIR were superior to 3D-IR sequences (global quality, estimated coefficient IR > early-PSIR : -2.37 CI = [-3.46 ; -1.38], prob(coef > 0) = 0 % and late-PSIR > IR : 3.12 CI = [0.62 ; 4.41], prob(coef > 0) = 100 %), LGE surface estimated coefficient IR > early-PSIR: -0.09 CI = [-1.11; -0.74], prob(coef > 0) = 0 % and late-PSIR > IR : 0.96 CI = [0.77; 1.15], prob(coef > 0) = 100 %). Probabilities for late PSIR being superior to early PSIR concerning global quality and CNR were over 90 %, regardless of the aetiological subgroup. CONCLUSIONS: In 3T cardiac MRI acquired with parallel RF transmission technique, 3D-PSIR is qualitatively and quantitatively superior to 3D-IR. KEY POINTS: * Late gadolinium enhancement is an essential part of a cardiac MRI examination * PSIR and IR sequences are the two possible options for LGE imaging * At 3T with parallel RF transmission, PSIR sequences are significantly better * One LGE sequence is sufficient, allowing an optimization of the acquisition time. FAU - Schultz, Anthony AU - Schultz A AD - Radiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. groseillou@hotmail.com. AD - Service de Radiologie, Nouvel Hopital Civil, 1 Place de l'Hopital, 67091, Strasbourg Cedex, France. groseillou@hotmail.com. FAU - Caspar, Thibault AU - Caspar T AD - Cardiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. FAU - Schaeffer, Mickael AU - Schaeffer M AD - Public Health and Biostatistics Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. FAU - Labani, Aissam AU - Labani A AD - Radiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. FAU - Jeung, Mi-Young AU - Jeung MY AD - Radiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. FAU - El Ghannudi, Soraya AU - El Ghannudi S AD - Radiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. FAU - Roy, Catherine AU - Roy C AD - Radiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. FAU - Ohana, Mickael AU - Ohana M AD - Radiology Department, Nouvel Hopital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. AD - iCube Laboratory, Universite de Strasbourg / CNRS, UMR 7357, 67400, Illkirch, France. LA - eng PT - Journal Article DEP - 20150915 PL - Germany TA - Eur Radiol JT - European radiology JID - 9114774 RN - 0 (Contrast Media) RN - 0 (Organometallic Compounds) RN - 1BJ477IO2L (gadobutrol) SB - IM MH - Adult MH - Aged MH - Bayes Theorem MH - Cardiomyopathies/*diagnostic imaging MH - Contrast Media MH - Female MH - Humans MH - Imaging, Three-Dimensional/methods MH - Magnetic Resonance Imaging/methods MH - Male MH - Middle Aged MH - Myocardial Ischemia/*diagnostic imaging MH - Myocarditis/*diagnostic imaging MH - Organometallic Compounds MH - Probability MH - Prospective Studies OTO - NOTNLM OT - Cardiac imaging techniques OT - Late gadolinium enhancement OT - Magnetic resonance imaging OT - Parallel radiofrequency transmission OT - Phase-sensitive inversion recovery EDAT- 2015/09/17 06:00 MHDA- 2017/02/28 06:00 CRDT- 2015/09/17 06:00 PHST- 2015/03/26 00:00 [received] PHST- 2015/09/02 00:00 [accepted] PHST- 2015/08/10 00:00 [revised] PHST- 2015/09/17 06:00 [entrez] PHST- 2015/09/17 06:00 [pubmed] PHST- 2017/02/28 06:00 [medline] AID - 10.1007/s00330-015-4002-y [pii] AID - 10.1007/s00330-015-4002-y [doi] PST - ppublish SO - Eur Radiol. 2016 Jun;26(6):1547-55. doi: 10.1007/s00330-015-4002-y. Epub 2015 Sep 15.