PMID- 2637604
OWN - NLM
STAT- MEDLINE
DCOM- 19900716
LR  - 20211203
IS  - 0001-6578 (Print)
IS  - 0001-6578 (Linking)
VI  - 30
IP  - 4
DP  - 1989 Jul-Aug
TI  - [Renal involvement in anaphylactoid purpura with particular reference to serum 
      immunoglobulin].
PG  - 240-7
AB  - Eighty-eight children of anaphylactoid purpura were studied in the Department of 
      Pediatrics from September 1979 to September 1987. Fifty-one children without 
      renal involvement recovered rapidly. Seven children with hematuria or proteinuria 
      and fourteen children with both manifestations recovered fully within six weeks 
      also. Two patients with hematuria and proteinuria recovered two months and four 
      months, respectively, after diagnosis. Ten children had persistent hematuria and 
      proteinuria lasting for more than six months; of these five children recovered 
      and four improved; one child died of intracranial hemorrhage and severe 
      infection. Nephrotic syndrome was noted in five children. Most of them (greater 
      than 80%) had persistent proteinuria more than six months. Incidence of renal 
      involvement was correlated with age. Older children especially those of more than 
      nine years old had a higher incidence rate (p less than 0.005). Serum 
      immunoglobulin A (IgA) and immunoglobulin E (IgE) levels were significantly 
      elevated in 44.7% and 36.4% of patients respectively, but neither influenced the 
      incidence of renal involvement or prognosis of renal disease. Elevated serum IgA 
      and IgE levels in acute stage were significantly reduced in 100% and 83% of 
      children when they were followed in convalescent stage (p less than 0.05). The 
      role of IgE deserves further study. Antinuclear antibody was positive in two 
      children without nephritis. Hypertension was noted in fifteen children, all with 
      renal involvement. Hypertension appears to be a good indicator for renal 
      involvement. Antistreptolysin O titer was elevated in 31.7% of children, but had 
      no significant correlation with incidence of renal involvement.
FAU - Chiou, S S
AU  - Chiou SS
FAU - Chang, T T
AU  - Chang TT
FAU - Perng, J J
AU  - Perng JJ
FAU - Chen, T S
AU  - Chen TS
LA  - chi
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi
JT  - Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er 
      ke yi xue hui
JID - 16210470R
RN  - 0 (Antibodies, Antinuclear)
RN  - 0 (Immunoglobulin A)
RN  - 0 (Immunoglobulins)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 9006-92-2 (Antistreptolysin)
SB  - IM
MH  - Adolescent
MH  - Antibodies, Antinuclear/metabolism
MH  - Antistreptolysin/metabolism
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - IgA Vasculitis/*complications/immunology
MH  - Immunoglobulin A/metabolism
MH  - Immunoglobulin E/metabolism
MH  - Immunoglobulins/*metabolism
MH  - Kidney Diseases/*etiology
MH  - Male
MH  - Prognosis
EDAT- 1989/07/01 00:00
MHDA- 1989/07/01 00:01
CRDT- 1989/07/01 00:00
PHST- 1989/07/01 00:00 [pubmed]
PHST- 1989/07/01 00:01 [medline]
PHST- 1989/07/01 00:00 [entrez]
PST - ppublish
SO  - Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1989 Jul-Aug;30(4):240-7.