PMID- 26385588
OWN - NLM
STAT- MEDLINE
DCOM- 20160921
LR  - 20161025
IS  - 1879-0518 (Electronic)
IS  - 0010-7824 (Linking)
VI  - 93
IP  - 1
DP  - 2016 Jan
TI  - Multipurpose prevention technologies for sexual and reproductive health: mapping 
      global needs for introduction of new preventive products.
PG  - 32-43
LID - S0010-7824(15)00577-6 [pii]
LID - 10.1016/j.contraception.2015.09.002 [doi]
AB  - OBJECTIVES: Worldwide, women face sexual and reproductive health (SRH) risks 
      including unintended pregnancy and sexually transmitted infections (STIs) 
      including HIV. Multipurpose prevention technologies (MPTs) combine protection 
      against two or more SRH risks into one product. Male and female condoms are the 
      only currently available MPT products, but several other forms of MPTs are in 
      development. We examined the global distribution of selected SRH issues to 
      determine where various risks have the greatest geographical overlap. STUDY 
      DESIGN: We examined four indicators relevant to MPTs in development: HIV 
      prevalence, herpes simplex virus type 2 prevalence (HSV-2), human papillomavirus 
      prevalence (HPV) and the proportion of women with unmet need for modern 
      contraception. Using ArcGIS Desktop, we mapped these indicators individually and 
      in combination on choropleth and graduated symbol maps. We conducted a principal 
      components analysis to reduce data and enable visual mapping of all four 
      indicators on one graphic to identify overlap. RESULTS: Our findings document the 
      greatest overlapping risks in Sub-Saharan Africa, and we specify countries in 
      greatest need by specific MPT indication. CONCLUSIONS: These results can inform 
      strategic planning for MPT introduction, market segmentation and demand 
      generation; data limitations also highlight the need for improved (non-HIV) STI 
      surveillance globally. IMPLICATIONS: MPTs are products in development with the 
      potential to empower women to prevent two or more SRH risks. Geographic analysis 
      of overlapping SRH risks demonstrates particularly high need in Sub-Saharan 
      Africa. This study can help to inform strategic planning for MPT introduction, 
      market segmentation and demand generation.
CI  - Copyright (c) 2016 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Schelar, Erin
AU  - Schelar E
AD  - Office of Population and Reproductive Health, United States Agency for 
      International Development, CP3-11090A, 1300 Pennsylvania Avenue NW, Washington, 
      DC 20523, USA. Electronic address: erin.schelar@gmail.com.
FAU - Polis, Chelsea B
AU  - Polis CB
AD  - Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 
      North Wolfe Street, Baltimore, MD 21205, USA.
FAU - Essam, Timothy
AU  - Essam T
AD  - Center for Data, Analysis and Research, United States Agency for International 
      Development, 1300 Pennsylvania Avenue NW, Washington, DC 20004, USA.
FAU - Looker, Katharine J
AU  - Looker KJ
AD  - School of Social and Community Medicine, University of Bristol, Oakfield House, 
      Oakfield Grove, Bristol BS8 2BN, United Kingdom.
FAU - Bruni, Laia
AU  - Bruni L
AD  - Catalan Institute of Oncology, Av. Gran Via de l'Hospitalet 199-203, 08908 
      l'Hospitalet de Llobregat (Barcelona), Spain.
FAU - Chrisman, Cara J
AU  - Chrisman CJ
AD  - Office of Population and Reproductive Health, United States Agency for 
      International Development, CP3-11090A, 1300 Pennsylvania Avenue NW, Washington, 
      DC 20523, USA.
FAU - Manning, Judy
AU  - Manning J
AD  - Office of Population and Reproductive Health, United States Agency for 
      International Development, CP3-11090A, 1300 Pennsylvania Avenue NW, Washington, 
      DC 20523, USA.
LA  - eng
GR  - R24 HD074034/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150916
PL  - United States
TA  - Contraception
JT  - Contraception
JID - 0234361
RN  - 0 (Contraceptive Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Africa/epidemiology
MH  - Americas/epidemiology
MH  - Asia/epidemiology
MH  - *Contraception
MH  - Contraceptive Agents/supply & distribution
MH  - Europe/epidemiology
MH  - Female
MH  - Geographic Information Systems
MH  - Geographic Mapping
MH  - Global Health
MH  - HIV Infections/*epidemiology/prevention & control
MH  - Health Services Needs and Demand
MH  - Herpes Genitalis/*epidemiology/prevention & control
MH  - Humans
MH  - Middle Aged
MH  - Oceania/epidemiology
MH  - Papillomavirus Infections/*epidemiology/prevention & control
MH  - Pregnancy
MH  - *Pregnancy, Unplanned
MH  - Prevalence
MH  - Young Adult
OTO - NOTNLM
OT  - HIV
OT  - HPV
OT  - HSV-2
OT  - Multipurpose prevention technologies
OT  - Unintended pregnancy
EDAT- 2015/09/20 06:00
MHDA- 2016/09/23 06:00
CRDT- 2015/09/20 06:00
PHST- 2015/03/14 00:00 [received]
PHST- 2015/09/03 00:00 [revised]
PHST- 2015/09/06 00:00 [accepted]
PHST- 2015/09/20 06:00 [entrez]
PHST- 2015/09/20 06:00 [pubmed]
PHST- 2016/09/23 06:00 [medline]
AID - S0010-7824(15)00577-6 [pii]
AID - 10.1016/j.contraception.2015.09.002 [doi]
PST - ppublish
SO  - Contraception. 2016 Jan;93(1):32-43. doi: 10.1016/j.contraception.2015.09.002. 
      Epub 2015 Sep 16.