PMID- 26390626
OWN - NLM
STAT- MEDLINE
DCOM- 20151001
LR  - 20161021
IS  - 1561-9125 (Print)
IS  - 1561-9125 (Linking)
VI  - 28
IP  - 1
DP  - 2015
TI  - [EVALUATED SERUM LEVELS OF BRAIN-DERIVED NEUROTROPHIC FACTOR IN MEN AND WOMEN 
      WITH CHRONIC BRAIN ISCHEMIA].
PG  - 146-7
AB  - We measured serum levels of brain-derived neurotrophic factor (BDNF) in 25 
      elderly women in 23 men-patients with chronic brain ischemia (CBI), and in 26 
      gender and age matched healthy controls. The serum levels of BDNF were 
      significantly lower in patients with CBI as compared to healthy controls. The 
      serum levels of BDNF were also lower in men with CBI (7815,14 x 10 ng/ml) in 
      comparison to women-patients (8466,05 x 10 ng/ml). The average serum levels of 
      BDNF in patients with CBI proved to be significantly correlated with kinesthetic 
      praxis disorders (p < 0.05), degree of cognitive impairment (p < 0.01), 
      depression level (p < 0.01), especially in men. The obtained data may be 
      important for individualization of therapeutic intervention.
FAU - Abramenko, Iu V
AU  - Abramenko IuV
FAU - Sliusar', T A
AU  - Sliusar' TA
FAU - Iakovlev, N A
AU  - Iakovlev NA
LA  - rus
PT  - English Abstract
PT  - Journal Article
PL  - Russia (Federation)
TA  - Adv Gerontol
JT  - Advances in gerontology = Uspekhi gerontologii
JID - 100971443
RN  - 0 (Biomarkers)
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Aging/*blood
MH  - Biomarkers/blood
MH  - Brain Ischemia/*blood/complications/physiopathology
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Chronic Disease
MH  - Cognition/*physiology
MH  - Cognition Disorders/blood/etiology/physiopathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
EDAT- 2015/09/24 06:00
MHDA- 2015/10/02 06:00
CRDT- 2015/09/23 06:00
PHST- 2015/09/23 06:00 [entrez]
PHST- 2015/09/24 06:00 [pubmed]
PHST- 2015/10/02 06:00 [medline]
PST - ppublish
SO  - Adv Gerontol. 2015;28(1):146-7.