PMID- 26391317
OWN - NLM
STAT- MEDLINE
DCOM- 20160211
LR  - 20181113
IS  - 1528-1167 (Electronic)
IS  - 0013-9580 (Print)
IS  - 0013-9580 (Linking)
VI  - 56
IP  - 11
DP  - 2015 Nov
TI  - Epileptic auras and their role in driving safety in people with epilepsy.
PG  - e182-5
LID - 10.1111/epi.13189 [doi]
AB  - The aim of our study was to evaluate the role of auras in preventing motor 
      vehicle accidents (MVAs) among patients with medically refractory epilepsy. The 
      Multicenter Study of Epilepsy Surgery database was used to perform a case-control 
      study by identifying patients who had seizures while driving that led to MVAs 
      (cases) and those who had seizures while driving without MVAs (controls). We 
      compared presence of reliable auras and other aura-related features between the 
      two groups. Two hundred fifteen of 553 patients reported having seizure(s) while 
      driving; 74 were identified as "controls" and 141 as "cases." The two groups had 
      similar demographic and clinical features. The presence of reliable auras was not 
      different between the two groups (67% in cases vs. 65% in controls; odds ratio 
      [OR] 0.89, 95% confidence interval [CI] 0.49-1.61, p = 0.76). In addition, the 
      groups did not differ in the proportion of patients who reported longer (>1 min) 
      auras (OR 0.7, 95% CI 0.28-1.76, p = 0.47), or who thought that their auras were 
      of sufficient duration to be protective (OR 1.19, 95% CI 0.62-2.00, p = 0.77). 
      Our study questions the long-held belief of a protective role of reliable auras 
      against MVAs in people with epilepsy.
CI  - Wiley Periodicals, Inc. (c) 2015 International League Against Epilepsy.
FAU - Punia, Vineet
AU  - Punia V
AD  - Departments of Neurology, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
FAU - Farooque, Pue
AU  - Farooque P
AD  - Departments of Neurology, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
FAU - Chen, William
AU  - Chen W
AD  - Departments of Neurology, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
FAU - Hirsch, Lawrence J
AU  - Hirsch LJ
AD  - Departments of Neurology, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
FAU - Berg, Anne T
AU  - Berg AT
AD  - Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, 
      Epilepsy Center, Chicago, Illinois, U.S.A.
AD  - Department of Pediatrics, Northwestern Memorial Feinberg School of Medicine, 
      Chicago, Illinois, U.S.A.
CN  - Multicenter Study of Epilepsy Surgery
FAU - Blumenfeld, Hal
AU  - Blumenfeld H
AD  - Departments of Neurology, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
AD  - Departments of Neurobiology, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
AD  - Departments of Neurosurgery, Yale University School of Medicine, New Haven, 
      Connecticut, U.S.A.
LA  - eng
GR  - R01 NS055829/NS/NINDS NIH HHS/United States
GR  - R01NS055829/NS/NINDS NIH HHS/United States
GR  - UL1 RR0249139/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20150922
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
SB  - IM
MH  - Accidents, Traffic/*prevention & control
MH  - *Automobile Driving/standards
MH  - Case-Control Studies
MH  - Databases, Factual
MH  - Epilepsy/*complications/*diagnosis
MH  - Humans
PMC - PMC4626266
MID - NIHMS715816
OTO - NOTNLM
OT  - Auras
OT  - Driving
OT  - Epilepsy
OT  - Motor vehicle accidents
OT  - Seizures
FIR - Spencer, Susan
IR  - Spencer S
FIR - Sperling, Michael
IR  - Sperling M
FIR - Bazil, Carl
IR  - Bazil C
FIR - Walczak, Thaddeus
IR  - Walczak T
FIR - Erba, Giuseppe
IR  - Erba G
FIR - Shinnar, Shlomo
IR  - Shinnar S
FIR - Devinsky, Orrin
IR  - Devinsky O
FIR - Vickrey, Barbara
IR  - Vickrey B
FIR - Berg, Anne
IR  - Berg A
EDAT- 2015/09/24 06:00
MHDA- 2016/02/13 06:00
PMCR- 2016/11/01
CRDT- 2015/09/23 06:00
PHST- 2015/08/11 00:00 [accepted]
PHST- 2015/09/23 06:00 [entrez]
PHST- 2015/09/24 06:00 [pubmed]
PHST- 2016/02/13 06:00 [medline]
PHST- 2016/11/01 00:00 [pmc-release]
AID - 10.1111/epi.13189 [doi]
PST - ppublish
SO  - Epilepsia. 2015 Nov;56(11):e182-5. doi: 10.1111/epi.13189. Epub 2015 Sep 22.