PMID- 26392801 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150922 LR - 20201001 IS - 1319-1683 (Print) IS - 2229-340X (Electronic) IS - 1319-1683 (Linking) VI - 22 IP - 3 DP - 2015 Sep-Dec TI - Eosinophilic ascites: A case report and literature review. PG - 183-5 LID - 10.4103/2230-8229.163042 [doi] AB - Eosinophilic gastroenteritis is a rare gastrointestinal (GI) disorder characterized by nonspecific GI symptoms, peripheral eosinophilia, and eosinophilic infiltration of the intestinal wall. The disorder is classified into mucosal, muscular, and sub-serosal types, depending on the clinical picture and the depth of eosinophilic infiltration within the GI wall. Sub-serosal disease, which is complicated by ascites, usually results in the most severe clinical form of eosinophilic gastroenteritis and requires early corticosteroid therapy. In such cases, a favorable outcome can be achieved after a short course of corticosteroids. We present the case of a 28-year-old female with diffuse abdominal pain and distention for 2 weeks. Her physical examination was significant for moderate ascites. Initial work-up demonstrated severe peripheral blood eosinophilia, normal liver function tests, and elevated serum immunoglobulin E (IgE). Upper endoscopy, colonoscopy showed a thickening of the stomach and colon, and biopsies showed marked eosinophilic infiltration of the mucosa. Ascitic fluid analysis showed significant eosinophilia. Subsequent treatment with oral prednisone resulted in the normalization of laboratory and radiologic abnormalities 45 days after the start of the treatment. Despite its rarity, eosinophilic gastroenteritis needs to be recognized by the clinician because the disease is treatable, and timely diagnosis and initiation of treatment could be of major importance. FAU - Alsulaiman, Raed M AU - Alsulaiman RM AD - Department of Internal Medicine, King Fahad Hospital of the University, University of Dammam, Dammam, Kingdom of Saudi Arabia. LA - eng PT - Case Reports PL - India TA - J Family Community Med JT - Journal of family & community medicine JID - 100911100 PMC - PMC4558742 OTO - NOTNLM OT - Eosinophilic ascites OT - eosinophilic gastroenteritis OT - gastrointestinal disorder EDAT- 2015/09/24 06:00 MHDA- 2015/09/24 06:01 PMCR- 2015/09/01 CRDT- 2015/09/23 06:00 PHST- 2015/09/23 06:00 [entrez] PHST- 2015/09/24 06:00 [pubmed] PHST- 2015/09/24 06:01 [medline] PHST- 2015/09/01 00:00 [pmc-release] AID - JFCM-22-183 [pii] AID - 10.4103/2230-8229.163042 [doi] PST - ppublish SO - J Family Community Med. 2015 Sep-Dec;22(3):183-5. doi: 10.4103/2230-8229.163042.