PMID- 26394783
OWN - NLM
STAT- MEDLINE
DCOM- 20161005
LR  - 20181113
IS  - 1573-7292 (Electronic)
IS  - 1389-9600 (Linking)
VI  - 15
IP  - 1
DP  - 2016 Jan
TI  - Aortopulmonary window parathyroid gland causing primary hyperparathyroidism in 
      men type 1 syndrome.
PG  - 133-8
LID - 10.1007/s10689-015-9840-x [doi]
AB  - Primary hyperparathyroidism (HPT) is the most common endocrinopathy in Multiple 
      Endocrine Neoplasia type 1 (MEN1) syndrome. Supernumerary and/or ectopic 
      parathyroid glands, potentially causes of persistent or recurrent HPT after 
      surgery, have been previously described. However, this is the first ever 
      described case of ectopic parathyroid gland localized in the aortopulmunary 
      window causing HPT in MEN1. After a consistent concordant pre-operative imaging 
      assessment the patient, a 16 years old male affected by a severe hypercalcemia, 
      underwent surgery. The parathyroid was found very deeply near the tracheal 
      bifurcation, hidden by the aortic arch itself and for this reason not visible at 
      the beginning of the dissection but only after being identified by palpation for 
      its typical consistence. The intraoperative PTH decreased at normal level 10 min 
      after removal of the ectopic gland. The patient remained with normal value of 
      calcemia and PTH during the 10 months of follow-up.
FAU - Tonelli, Francesco
AU  - Tonelli F
AD  - Department of Surgery and Translational Medicine, University of Florence, Largo 
      Brambilla 3, 50139, Florence, Italy. fmed@libero.it.
FAU - Biagini, Carlo
AU  - Biagini C
AD  - Signa Diagnostic Centre of Public Health Assistence, Florence, Italy.
FAU - Giudici, Francesco
AU  - Giudici F
AD  - Department of Surgery and Translational Medicine, University of Florence, Largo 
      Brambilla 3, 50139, Florence, Italy.
FAU - Cioppi, Federica
AU  - Cioppi F
AD  - Department of Surgery and Translational Medicine, University of Florence, Largo 
      Brambilla 3, 50139, Florence, Italy.
FAU - Brandi, Maria Luisa
AU  - Brandi ML
AD  - Department of Surgery and Translational Medicine, University of Florence, Largo 
      Brambilla 3, 50139, Florence, Italy.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Netherlands
TA  - Fam Cancer
JT  - Familial cancer
JID - 100898211
SB  - IM
MH  - Adolescent
MH  - Choristoma/*pathology
MH  - Humans
MH  - Hyperparathyroidism, Primary/*etiology
MH  - Male
MH  - Mediastinum/*pathology
MH  - Multiple Endocrine Neoplasia Type 1/*complications
MH  - *Parathyroid Glands
OTO - NOTNLM
OT  - Aortopulmonary window
OT  - MEN1
OT  - PHPT
OT  - Primary hyperparathyroidism
OT  - Surgery
EDAT- 2015/09/24 06:00
MHDA- 2016/10/07 06:00
CRDT- 2015/09/24 06:00
PHST- 2015/09/24 06:00 [entrez]
PHST- 2015/09/24 06:00 [pubmed]
PHST- 2016/10/07 06:00 [medline]
AID - 10.1007/s10689-015-9840-x [pii]
AID - 10.1007/s10689-015-9840-x [doi]
PST - ppublish
SO  - Fam Cancer. 2016 Jan;15(1):133-8. doi: 10.1007/s10689-015-9840-x.