PMID- 26398580 OWN - NLM STAT- MEDLINE DCOM- 20171012 LR - 20190221 IS - 1536-481X (Electronic) IS - 1057-0829 (Linking) VI - 25 IP - 6 DP - 2016 Jun TI - Secondary Epiretinal Membrane After Trabeculectomy. PG - e576-80 LID - 10.1097/IJG.0000000000000326 [doi] AB - PURPOSE: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy. METHODS: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded. RESULTS: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P=0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P=0.09). CONCLUSION: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation. FAU - Vieira, Luisa AU - Vieira L AD - *Department of Ophthalmology, Central Lisbon Hospital Center daggerInstitute of Pharmacology and Neurosciences, Faculty of Medicine, University of Lisbon double daggerNOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal. FAU - Cabugueira, Ana AU - Cabugueira A FAU - Borges, Barbara AU - Borges B FAU - Carvalho, Vanessa AU - Carvalho V FAU - Noronha, Manuel AU - Noronha M FAU - Abegao Pinto, Luis AU - Abegao Pinto L FAU - Reina, Maria AU - Reina M FAU - Dutra Medeiros, Marco AU - Dutra Medeiros M LA - eng PT - Journal Article PL - United States TA - J Glaucoma JT - Journal of glaucoma JID - 9300903 SB - IM MH - Adult MH - Aged MH - Epiretinal Membrane/diagnosis/epidemiology/*etiology MH - Female MH - Follow-Up Studies MH - Glaucoma, Open-Angle/physiopathology/*surgery MH - Humans MH - Incidence MH - Intraocular Pressure MH - Male MH - Middle Aged MH - Portugal/epidemiology MH - Postoperative Complications/epidemiology MH - Retrospective Studies MH - Time Factors MH - Tomography, Optical Coherence MH - Trabeculectomy/*adverse effects MH - *Visual Acuity EDAT- 2015/09/24 06:00 MHDA- 2017/10/13 06:00 CRDT- 2015/09/24 06:00 PHST- 2015/09/24 06:00 [entrez] PHST- 2015/09/24 06:00 [pubmed] PHST- 2017/10/13 06:00 [medline] AID - 10.1097/IJG.0000000000000326 [doi] PST - ppublish SO - J Glaucoma. 2016 Jun;25(6):e576-80. doi: 10.1097/IJG.0000000000000326.