PMID- 26411958
OWN - NLM
STAT- MEDLINE
DCOM- 20160201
LR  - 20221207
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Print)
IS  - 0007-1145 (Linking)
VI  - 114
IP  - 10
DP  - 2015 Nov 28
TI  - The effect of macronutrients on glycaemic control: a systematic review of dietary 
      randomised controlled trials in overweight and obese adults with type 2 diabetes 
      in which there was no difference in weight loss between treatment groups.
PG  - 1656-66
LID - 10.1017/S0007114515003475 [doi]
AB  - Weight loss is crucial for treating type 2 diabetes mellitus (T2DM). It remains 
      unclear which dietary intervention is best for optimising glycaemic control, or 
      whether weight loss itself is the main reason behind observed improvements. The 
      objective of this study was to assess the effects of various dietary 
      interventions on glycaemic control in overweight and obese adults with T2DM when 
      controlling for weight loss between dietary interventions. A systematic review of 
      randomised controlled trials (RCT) was conducted. Electronic searches of Medline, 
      Embase, Cinahl and Web of Science databases were conducted. Inclusion criteria 
      included RCT with minimum 6 months duration, with participants having BMI>/=25.0 
      kg/m2, a diagnosis of T2DM using HbA1c, and no statistically significant 
      difference in mean weight loss at the end point of intervention between dietary 
      arms. Results showed that eleven studies met the inclusion criteria. Only four 
      RCT indicated the benefit of a particular dietary intervention over another in 
      improving HbA1c levels, including the Mediterranean, vegan and low glycaemic 
      index (GI) diets. However the findings from one of the four studies showing a 
      significant benefit are questionable because of failure to control for diabetes 
      medications and poor adherence to the prescribed diets. In conclusion there is 
      currently insufficient evidence to suggest that any particular diet is superior 
      in treating overweight and obese patients with T2DM. Although the Mediterranean, 
      vegan and low-GI diets appear to be promising, further research that controls for 
      weight loss and the effects of diabetes medications in larger samples is needed.
FAU - Emadian, Amir
AU  - Emadian A
AD  - 1School of Sport,Exercise and Rehabilitation Sciences,University of 
      Birmingham,Edgbaston,Birmingham B15 2TT,UK.
FAU - Andrews, Rob C
AU  - Andrews RC
AD  - 2School of Clinical Sciences,University of Bristol,Bristol BS10 5NB,UK.
FAU - England, Clare Y
AU  - England CY
AD  - 3Centre for Exercise,Nutrition and Health Sciences,University of Bristol,Bristol 
      BS8 1TZ,UK.
FAU - Wallace, Victoria
AU  - Wallace V
AD  - 4School of Psychology,University of Birmingham,Edgbaston,Birmingham B15 2TT,UK.
FAU - Thompson, Janice L
AU  - Thompson JL
AD  - 1School of Sport,Exercise and Rehabilitation Sciences,University of 
      Birmingham,Edgbaston,Birmingham B15 2TT,UK.
LA  - eng
GR  - CAT CDRF 10-017/DH_/Department of Health/United Kingdom
GR  - MR/K00414X/1/MRC_/Medical Research Council/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PT  - Systematic Review
DEP - 20150928
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Blood Glucose/*analysis
MH  - Diabetes Mellitus, Type 2/complications/*diet therapy
MH  - *Diet
MH  - Diet, Mediterranean
MH  - Diet, Vegan
MH  - Glycated Hemoglobin/analysis
MH  - Glycemic Index
MH  - Humans
MH  - MEDLINE
MH  - Obesity/complications/*diet therapy
MH  - Overweight/complications/*diet therapy
MH  - Randomized Controlled Trials as Topic
MH  - *Weight Loss
PMC - PMC4657029
OTO - NOTNLM
OT  - ADA American Diabetes Association
OT  - Diet
OT  - GI glycaemic index
OT  - GL glycaemic load
OT  - LCM low carbohydrate Mediterranean
OT  - Systematic reviews
OT  - T2DM type 2 diabetes mellitus
OT  - Type 2 diabetes
OT  - Weight loss
EDAT- 2015/09/29 06:00
MHDA- 2016/02/02 06:00
PMCR- 2015/11/24
CRDT- 2015/09/29 06:00
PHST- 2015/09/29 06:00 [entrez]
PHST- 2015/09/29 06:00 [pubmed]
PHST- 2016/02/02 06:00 [medline]
PHST- 2015/11/24 00:00 [pmc-release]
AID - S0007114515003475 [pii]
AID - 00347 [pii]
AID - 10.1017/S0007114515003475 [doi]
PST - ppublish
SO  - Br J Nutr. 2015 Nov 28;114(10):1656-66. doi: 10.1017/S0007114515003475. Epub 2015 
      Sep 28.