PMID- 26412080 OWN - NLM STAT- MEDLINE DCOM- 20160413 LR - 20181202 IS - 1573-2959 (Electronic) IS - 0167-6369 (Linking) VI - 187 IP - 10 DP - 2015 Oct TI - Residue behavior and risk assessment of mixed formulation of imidacloprid and chlorfenapyr in chieh-qua under field conditions. PG - 650 LID - 10.1007/s10661-015-4846-2 [doi] AB - A simple and rapid method based on high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was developed for the simultaneous determination of imidacloprid and chlorfenapyr residues in chieh-qua. Field trials were designed to investigate the dissipation and terminal residue behavior of the mixed formulation of imidacloprid and chlorfenapyr in chieh-qua in Guangzhou and Nanning areas. Risk assessment was performed by calculating the risk quotient (RQ) values. The developed analytical method exhibited recoveries of 89.9-110.3% with relative standard deviations (RSDs) of 2.8-12.5% at the spiked levels of 0.01, 0.10, and 1.00 mg/kg. The limit of detection (LOD) was 0.003 mg/kg, and the limit of quantification (LOQ) was 0.01 mg/kg for both imidacloprid and chlorfenapyr. It was found that the half-lives of imidacloprid in chieh-qua under field conditions were 3.3 and 3.5 days in Guangzhou and Nanning at a dose of 180 g ai/ha, while the half-lives of chlorfenapyr were 3.3 and 2.6 days, respectively. The terminal residues of imidacloprid and chlorfenapyr were from 0.01 to 0.21 mg/kg and from 0.01 to 0.46 mg/kg, respectively. Results of dietary exposure assessment showed that the RQ values were much lower than 1, indicating that the risk of imidacloprid and chlorfenapyr applied in chieh-qua was negligible to human health under recommended dosage and good agricultural practices. The proposed study would provide guidance for safe and reasonable use of imidacloprid and chlorfenapyr in chieh-qua cultivation in China. FAU - Huang, Jian Xiang AU - Huang JX AD - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. AD - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, Ministry of Agriculture, Guangzhou, 510640, China. AD - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), Ministry of Agriculture, Guangzhou, 510640, China. FAU - Liu, Cong Yun AU - Liu CY AD - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. AD - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, Ministry of Agriculture, Guangzhou, 510640, China. AD - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), Ministry of Agriculture, Guangzhou, 510640, China. FAU - Lu, Da Hai AU - Lu DH AD - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. AD - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, Ministry of Agriculture, Guangzhou, 510640, China. AD - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), Ministry of Agriculture, Guangzhou, 510640, China. FAU - Chen, Jia Jia AU - Chen JJ AD - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. AD - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, Ministry of Agriculture, Guangzhou, 510640, China. AD - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), Ministry of Agriculture, Guangzhou, 510640, China. FAU - Deng, Yi Cai AU - Deng YC AD - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. AD - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, Ministry of Agriculture, Guangzhou, 510640, China. AD - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), Ministry of Agriculture, Guangzhou, 510640, China. FAU - Wang, Fu Hua AU - Wang FH AD - Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. wfhwqs@163.com. AD - Key Laboratory of Testing and Evaluation for Agro-product Quality and Safety, Ministry of Agriculture, Guangzhou, 510640, China. wfhwqs@163.com. AD - Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou), Ministry of Agriculture, Guangzhou, 510640, China. wfhwqs@163.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150928 PL - Netherlands TA - Environ Monit Assess JT - Environmental monitoring and assessment JID - 8508350 RN - 0 (Imidazoles) RN - 0 (Neonicotinoids) RN - 0 (Nitro Compounds) RN - 0 (Pesticide Residues) RN - 0 (Pyrethrins) RN - 3BN7M937V8 (imidacloprid) RN - NWI20P05EB (chlorfenapyr) SB - IM MH - Agriculture/*methods MH - China MH - Chromatography, High Pressure Liquid/methods MH - Cucurbitaceae/*chemistry MH - Environmental Monitoring/*methods MH - Imidazoles/*analysis MH - Limit of Detection MH - Neonicotinoids MH - Nitro Compounds/*analysis MH - Pesticide Residues/*analysis MH - Pyrethrins/*analysis MH - Risk Assessment MH - Tandem Mass Spectrometry/methods OTO - NOTNLM OT - Chieh-qua OT - Chlorfenapyr OT - Imidacloprid OT - Residue OT - Risk assessment EDAT- 2015/09/29 06:00 MHDA- 2016/04/14 06:00 CRDT- 2015/09/29 06:00 PHST- 2015/03/23 00:00 [received] PHST- 2015/09/04 00:00 [accepted] PHST- 2015/09/29 06:00 [entrez] PHST- 2015/09/29 06:00 [pubmed] PHST- 2016/04/14 06:00 [medline] AID - 10.1007/s10661-015-4846-2 [pii] AID - 10.1007/s10661-015-4846-2 [doi] PST - ppublish SO - Environ Monit Assess. 2015 Oct;187(10):650. doi: 10.1007/s10661-015-4846-2. Epub 2015 Sep 28.