PMID- 26419001
OWN - NLM
STAT- MEDLINE
DCOM- 20151222
LR  - 20161125
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 32
IP  - 5
DP  - 2015 Oct
TI  - [Progress of molecular genetics research on rheumatoid arthritis].
PG  - 728-33
LID - 10.3760/cma.j.issn.1003-9406.2015.05.026 [doi]
AB  - Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disorder that 
      principally attacks flexible joints and synovia. The precise pathogenesis of RA 
      remains unclear, and genetic factors probably play an important role in its 
      etiology. In addition to genes from human leukocyte antigen (HLA) region, such as 
      HLA-DRB, genes from non-HLA region, such as TIM-3, PTPN22, TRAF1/C5, STAT4, CCR5, 
      PADI4 and FCGR2A may also contribute to its susceptibility. The advance in 
      molecular genetics research on RA is reviewed here.
FAU - Chen, Rong
AU  - Chen R
AD  - Department of Microbiology and Immunology, North Sichuan Medical College, 
      Nanchong, Sichuan 637000, P.R. China. Email: zdd25@sina.com.
FAU - Luo, Jiaming
AU  - Luo J
FAU - Zhang, Dingding
AU  - Zhang D
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
RN  - 0 (FCGR2A protein, human)
RN  - 0 (HAVCR2 protein, human)
RN  - 0 (HLA-DRB1 Chains)
RN  - 0 (Hepatitis A Virus Cellular Receptor 2)
RN  - 0 (Membrane Proteins)
RN  - 0 (Receptors, IgG)
RN  - EC 3.1.3.48 (PTPN22 protein, human)
RN  - EC 3.1.3.48 (Protein Tyrosine Phosphatase, Non-Receptor Type 22)
SB  - IM
MH  - Arthritis, Rheumatoid/*genetics
MH  - Exome
MH  - Genetic Predisposition to Disease
MH  - HLA-DRB1 Chains/genetics
MH  - Hepatitis A Virus Cellular Receptor 2
MH  - Humans
MH  - Membrane Proteins/genetics
MH  - Protein Tyrosine Phosphatase, Non-Receptor Type 22/genetics
MH  - Receptors, IgG/genetics
EDAT- 2015/09/30 06:00
MHDA- 2015/12/23 06:00
CRDT- 2015/09/30 06:00
PHST- 2015/09/30 06:00 [entrez]
PHST- 2015/09/30 06:00 [pubmed]
PHST- 2015/12/23 06:00 [medline]
AID - 940632154 [pii]
AID - 10.3760/cma.j.issn.1003-9406.2015.05.026 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Oct;32(5):728-33. doi: 
      10.3760/cma.j.issn.1003-9406.2015.05.026.