PMID- 26425012
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151001
LR  - 20200930
IS  - 0972-2327 (Print)
IS  - 1998-3549 (Electronic)
IS  - 0972-2327 (Linking)
VI  - 18
IP  - 3
DP  - 2015 Jul-Sep
TI  - Treatment of pediatric chronic inflammatory demyelinating polyneuropathy: 
      Challenges, controversies and questions.
PG  - 327-30
LID - 10.4103/0972-2327.160065 [doi]
AB  - Pediatric chronic inflammatory demyelinating polyneuropathy (CIDP) is an uncommon 
      acquired disorder of unknown cause, presumed to have an immunological basis. We 
      report 20 patients seen at Children's Hospital Los Angeles over a period of 10 
      years. The outcome of our patients was favorable in a vast majority with good 
      response to various treatments instituted. However, residual neurologic deficit 
      was common. The choice of treatment modality was empirical and selected by the 
      treating neurologist. Intravenous immunoglobulin (IVIG) and corticosteroids were 
      most commonly utilized for treatment. Plasmapheresis, mycophenolate mofetil, 
      rituximab, cyclophosphamide, azathioprine, and abatacept were added if the 
      patients were refractory to IVIG or became corticosteroid dependent. The spectrum 
      of disease severity ranged from a single monophasic episode, to multiphasic with 
      infrequent relapses with good response to IVIG, to progressive disease refractory 
      to multiple therapies.
FAU - Desai, Jay
AU  - Desai J
AD  - Division of Neurology, Children's Hospital Los Angeles, Keck School of Medicine 
      of University of Southern California, United States of America.
FAU - Ramos-Platt, Leigh
AU  - Ramos-Platt L
AD  - Division of Neurology, Children's Hospital Los Angeles, Keck School of Medicine 
      of University of Southern California, United States of America.
FAU - Mitchell, Wendy G
AU  - Mitchell WG
AD  - Division of Neurology, Children's Hospital Los Angeles, Keck School of Medicine 
      of University of Southern California, United States of America.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Ann Indian Acad Neurol
JT  - Annals of Indian Academy of Neurology
JID - 101273955
PMC - PMC4564469
OTO - NOTNLM
OT  - CIDP
OT  - Childhood
OT  - children
OT  - chronic inflammatory demyelinating polyneuropathy
OT  - pediatric
COIS- Conflicts of Interest: None declared.
EDAT- 2015/10/02 06:00
MHDA- 2015/10/02 06:01
PMCR- 2015/07/01
CRDT- 2015/10/02 06:00
PHST- 2015/10/02 06:00 [entrez]
PHST- 2015/10/02 06:00 [pubmed]
PHST- 2015/10/02 06:01 [medline]
PHST- 2015/07/01 00:00 [pmc-release]
AID - AIAN-18-327 [pii]
AID - 10.4103/0972-2327.160065 [doi]
PST - ppublish
SO  - Ann Indian Acad Neurol. 2015 Jul-Sep;18(3):327-30. doi: 10.4103/0972-2327.160065.