PMID- 26431305 OWN - NLM STAT- MEDLINE DCOM- 20160429 LR - 20151003 IS - 2325-8179 (Electronic) IS - 2325-8160 (Linking) VI - 46 IP - 8 DP - 2015 Sep TI - Outer Retinal Changes Preceding Secondary Macular Hole Formation Years After Vitreomacular Traction Release Demonstrated on Spectral-Domain OCT. PG - 880-2 LID - 10.3928/23258160-20150909-14 [doi] AB - This report describes changes documented on spectral-domain optical coherence tomography (SD-OCT) in the right eye of a 58-year-old woman who eventually developed a secondary full-thickness macular hole (FTMH). She had a history of vitreomacular traction (VMT) that had resolved spontaneously with a complete posterior vitreous detachment. Despite VMT resolution, a hyperreflective band from the internal to the external limiting membrane and evidence of photoreceptor disruption persisted on SD-OCT for 2 years, at which point an FTMH developed. Despite VMT release, the unexpected FTMH coupled with the preceding outer retinal changes suggest persistent secondary damage to Muller cells as a potential factor. CI - Copyright 2015, SLACK Incorporated. FAU - Chin, Adam T AU - Chin AT FAU - Bonini Filho, Marco A AU - Bonini Filho MA FAU - de Carlo, Talisa E AU - de Carlo TE FAU - Adhi, Mehreen AU - Adhi M FAU - Duker, Jay S AU - Duker JS LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Ophthalmic Surg Lasers Imaging Retina JT - Ophthalmic surgery, lasers & imaging retina JID - 101599215 SB - IM MH - Female MH - Humans MH - Middle Aged MH - *Postoperative Complications MH - Remission, Spontaneous MH - Retina/*pathology MH - Retinal Diseases/*physiopathology MH - Retinal Perforations/*diagnosis/etiology/surgery MH - Tissue Adhesions/physiopathology MH - *Tomography, Optical Coherence MH - Visual Acuity/physiology MH - Vitreous Body/physiopathology MH - Vitreous Detachment/*physiopathology EDAT- 2015/10/03 06:00 MHDA- 2016/04/30 06:00 CRDT- 2015/10/03 06:00 PHST- 2015/03/25 00:00 [received] PHST- 2015/08/07 00:00 [accepted] PHST- 2015/10/03 06:00 [entrez] PHST- 2015/10/03 06:00 [pubmed] PHST- 2016/04/30 06:00 [medline] AID - 10.3928/23258160-20150909-14 [doi] PST - ppublish SO - Ophthalmic Surg Lasers Imaging Retina. 2015 Sep;46(8):880-2. doi: 10.3928/23258160-20150909-14.