PMID- 26433529
OWN - NLM
STAT- MEDLINE
DCOM- 20160711
LR  - 20210416
IS  - 1440-1592 (Electronic)
IS  - 1323-8930 (Linking)
VI  - 64
IP  - 4
DP  - 2015 Oct
TI  - Common food allergens and their IgE-binding epitopes.
PG  - 332-43
LID - S1323-8930(15)00146-X [pii]
LID - 10.1016/j.alit.2015.06.009 [doi]
AB  - Food allergy is an adverse immune response to certain kinds of food. Although any 
      food can cause allergic reactions, chicken egg, cow's milk, wheat, shellfish, 
      fruit, and buckwheat account for 75% of food allergies in Japan. 
      Allergen-specific immunoglobulin E (IgE) antibodies play a pivotal role in the 
      development of food allergy. Recent advances in molecular biological techniques 
      have enabled the efficient analysis of food allergens. As a result, many food 
      allergens have been identified, and their molecular structure and IgE-binding 
      epitopes have also been identified. Studies of allergens have demonstrated that 
      IgE antibodies specific to allergen components and/or the peptide epitopes are 
      good indicators for the identification of patients with food allergy, prediction 
      of clinical severity and development of tolerance. In this review, we summarize 
      our current knowledge regarding the allergens and IgE epitopes in the 
      well-researched allergies to chicken egg, cow's milk, wheat, shrimp, and peanut.
CI  - Copyright (c) 2015 Japanese Society of Allergology. Production and hosting by 
      Elsevier B.V. All rights reserved.
FAU - Matsuo, Hiroaki
AU  - Matsuo H
AD  - Department of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, 
      Japan. Electronic address: hmatsuo@hiroshima-u.ac.jp.
FAU - Yokooji, Tomoharu
AU  - Yokooji T
AD  - Department of Pathophysiology and Therapeutics, Institute of Biomedical and 
      Health Sciences, Hiroshima University, Hiroshima, Japan.
FAU - Taogoshi, Takanori
AU  - Taogoshi T
AD  - Department of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, 
      Japan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20150729
PL  - England
TA  - Allergol Int
JT  - Allergology international : official journal of the Japanese Society of 
      Allergology
JID - 9616296
RN  - 0 (Allergens)
RN  - 0 (Epitopes)
RN  - 0 (Epitopes, T-Lymphocyte)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens/classification/*immunology
MH  - Animals
MH  - Epitopes/chemistry/*immunology
MH  - Epitopes, T-Lymphocyte/immunology
MH  - Food Hypersensitivity/diagnosis/*immunology
MH  - Humans
MH  - Immunoglobulin E/*immunology
MH  - Protein Binding/immunology
MH  - T-Lymphocyte Subsets/immunology/metabolism
OTO - NOTNLM
OT  - Allergen
OT  - Diagnosis
OT  - Epitope
OT  - Food allergy
OT  - Immunoglobulin E
EDAT- 2015/10/05 06:00
MHDA- 2016/07/12 06:00
CRDT- 2015/10/05 06:00
PHST- 2015/05/06 00:00 [received]
PHST- 2015/06/18 00:00 [revised]
PHST- 2015/06/23 00:00 [accepted]
PHST- 2015/10/05 06:00 [entrez]
PHST- 2015/10/05 06:00 [pubmed]
PHST- 2016/07/12 06:00 [medline]
AID - S1323-8930(15)00146-X [pii]
AID - 10.1016/j.alit.2015.06.009 [doi]
PST - ppublish
SO  - Allergol Int. 2015 Oct;64(4):332-43. doi: 10.1016/j.alit.2015.06.009. Epub 2015 
      Jul 29.