PMID- 26434328
OWN - NLM
STAT- MEDLINE
DCOM- 20160420
LR  - 20181202
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 132
IP  - 1
DP  - 2012 May 1
TI  - Simultaneous determination of eight underivatised biogenic amines in fish by 
      solid phase extraction and liquid chromatography-tandem mass spectrometry.
PG  - 537-43
LID - S0308-8146(11)01506-8 [pii]
LID - 10.1016/j.foodchem.2011.10.054 [doi]
AB  - Biogenic amines on fish tissue are formed as a result of bacterial contamination 
      and spoilage during storage. A new method based on liquid chromatography (LC) and 
      tandem mass spectrometry (MS/MS) using a triple quadrupole (QqQ) analyser was 
      developed for the analysis of eight biogenic amines (cadaverine, histamine, 
      phenylethylamine, putrescine, spermine, spermidine, tyramine and tryptamine) in 
      fish tissues. Sample preparation was performed by extraction with trichloroacetic 
      acid 5% and solid phase extraction clean up with STRATA X cartridge. The MS/MS 
      method was validated and compared with a method based on the analysis of dansyl 
      derivatives by LC and fluorescence detector (FD). MS/MS achieved higher 
      sensitivity (from 0.02mgkg(-1) for spermidine and phenylethylamine to 0.2mgkg(-1) 
      for spermine) when compared to FD (from 1mgkg(-1) for putrescine and tyramine to 
      4mgkg(-1) for histamine); MS/MS method showed higher precision too, with intraday 
      relative standard deviations (RSDs) from 1% to 4% with respect to those obtained 
      with FD method (from 3% to 17%). Recovery study was conducted at two different 
      fortification levels and the average ranged from 71% to 93% for all of the 
      studied compounds with RSDs lower than 18%. Matrix-matched standards were used to 
      counteract matrix effect observed in MS/MS determination. The applicability of 
      the method was demonstrated by the analysis of biogenic amines in fish obtained 
      from commercials of Valencia.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Sagratini, G
AU  - Sagratini G
AD  - Scuola di Scienze del Farmaco e dei Prodotti della Salute, Universita di 
      Camerino, via S. Agostino 1, 62032 Camerino, Italy.
FAU - Fernandez-Franzon, M
AU  - Fernandez-Franzon M
AD  - Laboratori de Bromatologia i Toxicologia, Facultat de Farmacia, Universitat de 
      Valencia, Av. Vicent Andres Estelles s/n, 46100 Burjassot, Spain. Electronic 
      address: monica.fernandez@uv.es.
FAU - De Berardinis, F
AU  - De Berardinis F
AD  - Scuola di Scienze del Farmaco e dei Prodotti della Salute, Universita di 
      Camerino, via S. Agostino 1, 62032 Camerino, Italy.
FAU - Font, G
AU  - Font G
AD  - Laboratori de Bromatologia i Toxicologia, Facultat de Farmacia, Universitat de 
      Valencia, Av. Vicent Andres Estelles s/n, 46100 Burjassot, Spain.
FAU - Vittori, S
AU  - Vittori S
AD  - Scuola di Scienze del Farmaco e dei Prodotti della Salute, Universita di 
      Camerino, via S. Agostino 1, 62032 Camerino, Italy.
FAU - Manes, J
AU  - Manes J
AD  - Laboratori de Bromatologia i Toxicologia, Facultat de Farmacia, Universitat de 
      Valencia, Av. Vicent Andres Estelles s/n, 46100 Burjassot, Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111104
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Biogenic Amines)
SB  - IM
MH  - Animals
MH  - Biogenic Amines/analysis/*chemistry
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Chromatography, Liquid/methods
MH  - Fishes/*metabolism
MH  - Solid Phase Extraction/*methods
MH  - Tandem Mass Spectrometry/*methods
OTO - NOTNLM
OT  - Biogenic amines
OT  - Fish
OT  - Liquid chromatography-tandem mass spectrometry
OT  - Solid phase extraction
EDAT- 2012/05/01 00:00
MHDA- 2016/04/21 06:00
CRDT- 2015/10/06 06:00
PHST- 2010/12/06 00:00 [received]
PHST- 2011/06/05 00:00 [revised]
PHST- 2011/10/17 00:00 [accepted]
PHST- 2015/10/06 06:00 [entrez]
PHST- 2012/05/01 00:00 [pubmed]
PHST- 2016/04/21 06:00 [medline]
AID - S0308-8146(11)01506-8 [pii]
AID - 10.1016/j.foodchem.2011.10.054 [doi]
PST - ppublish
SO  - Food Chem. 2012 May 1;132(1):537-43. doi: 10.1016/j.foodchem.2011.10.054. Epub 
      2011 Nov 4.