PMID- 26436683
OWN - NLM
STAT- MEDLINE
DCOM- 20160802
LR  - 20151215
IS  - 1096-0260 (Electronic)
IS  - 0091-7435 (Linking)
VI  - 81
DP  - 2015 Dec
TI  - Effects of a multi-component camp-based intervention on inflammatory markers and 
      adipokines in children: A randomized controlled trial.
PG  - 367-72
LID - S0091-7435(15)00299-6 [pii]
LID - 10.1016/j.ypmed.2015.09.014 [doi]
AB  - OBJECTIVE: To examine the effects of a multi-component camp-based intervention on 
      inflammatory markers and adipokines in children. METHODS: One hundred and fifteen 
      children were recruited in Odense, Denmark (2012-2014). The participants were 
      randomly allocated to either the day camp intervention arm (DCIA) or the standard 
      intervention arm (SIA). The intervention for the DCIA consisted of a 6-week 
      camp-based intervention and a 46-week family-based intervention. The SIA was 
      offered one weekly physical activity session for 6 weeks and one educational 
      meeting. C-reactive protein (CRP), monocyte chemoattractant protein-1 (MCP1), 
      leptin, and adiponectin were measured in serum at baseline, 6 weeks and 52 weeks. 
      RESULTS: In comparison with the SIA, the reductions in CRP (P=0.003) and leptin 
      (p<0.001) were larger in the DCIA at 6 weeks. The intervention effects on leptin 
      were significantly mediated by the changes in body fat mass. No intervention 
      effects on CRP and leptin were seen at 52 weeks. No between-group differences in 
      changes in MCP1 and adiponectin were observed at 6 weeks or 52 weeks. 
      CONCLUSIONS: The 6-week camp intervention resulted in reductions in CRP and 
      leptin. The intervention effects did not persist to 52 weeks. The intervention 
      effect on leptin was explained by changes in body fat mass.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Huang, Tao
AU  - Huang T
AD  - Center of Research in Childhood Health (RICH), Institute of Sports Science and 
      Clinical Biomechanics, University of Southern Denmark, Odense, Denmark. 
      Electronic address: thuang@health.sdu.dk.
FAU - Larsen, Kristian Traberg
AU  - Larsen KT
AD  - Center of Research in Childhood Health (RICH), Institute of Sports Science and 
      Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
FAU - Moller, Niels Christian
AU  - Moller NC
AD  - Center of Research in Childhood Health (RICH), Institute of Sports Science and 
      Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
FAU - Ried-Larsen, Mathias
AU  - Ried-Larsen M
AD  - The Center of Inflammation and Metabolism (CIM) and The Center for Physical 
      Activity Research (CFAS) at Rigshospitalet, Copenhagen, The Danish Diabetes 
      Academy, Odense, Denmark.
FAU - Frandsen, Ulrik
AU  - Frandsen U
AD  - SDU Muscle Research Cluster (SMRC), Institute of Sports Science and Clinical 
      Biomechanics, University of Southern Denmark, Odense, Denmark.
FAU - Andersen, Lars Bo
AU  - Andersen LB
AD  - Center of Research in Childhood Health (RICH), Institute of Sports Science and 
      Clinical Biomechanics, University of Southern Denmark, Odense, Denmark; 
      Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20151003
PL  - United States
TA  - Prev Med
JT  - Preventive medicine
JID - 0322116
RN  - 0 (Biomarkers)
RN  - 0 (CCL2 protein, human)
RN  - 0 (Chemokine CCL2)
RN  - 0 (Leptin)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Biomarkers/*blood
MH  - Body Mass Index
MH  - C-Reactive Protein/*analysis
MH  - Camping
MH  - Chemokine CCL2/*blood
MH  - Child
MH  - Denmark
MH  - Female
MH  - Humans
MH  - Leptin/*blood
MH  - Male
MH  - Obesity/*blood/therapy
MH  - Time Factors
MH  - Weight Reduction Programs
OTO - NOTNLM
OT  - Adipokines
OT  - Children
OT  - Inflammatory markers
OT  - Low-grade inflammation
OT  - Obesity
EDAT- 2015/10/06 06:00
MHDA- 2016/08/03 06:00
CRDT- 2015/10/06 06:00
PHST- 2015/03/06 00:00 [received]
PHST- 2015/09/23 00:00 [revised]
PHST- 2015/09/26 00:00 [accepted]
PHST- 2015/10/06 06:00 [entrez]
PHST- 2015/10/06 06:00 [pubmed]
PHST- 2016/08/03 06:00 [medline]
AID - S0091-7435(15)00299-6 [pii]
AID - 10.1016/j.ypmed.2015.09.014 [doi]
PST - ppublish
SO  - Prev Med. 2015 Dec;81:367-72. doi: 10.1016/j.ypmed.2015.09.014. Epub 2015 Oct 3.