PMID- 26439248 OWN - NLM STAT- MEDLINE DCOM- 20160809 LR - 20220410 IS - 1752-0371 (Electronic) IS - 1752-0363 (Linking) VI - 9 IP - 10 DP - 2015 TI - Monocyte/HDL-cholesterol ratio predicts the definite stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. PG - 967-77 LID - 10.2217/bmm.15.74 [doi] AB - AIM: We investigated the predictive value of monocyte count to HDL ratio (M/H ratio) for stent thrombosis (ST) in ST elevation myocardial infarction (STEMI). PATIENTS & METHODS: 1170 STEMI patients treated with primary PCI were followed-up for a median of 37.2 months. RESULTS: During follow-up, 112 patients were diagnosed as 'definite' ST. The rate of ST was significantly highest in the third M/H ratio tertile. In Cox regression analysis, adjusted for other factors, having an M/H ratio in third tertile had a 2.2-fold increased risk of ST. Kaplan-Meier analysis revealed the higher occurrence of ST in the third tertile compared with others (p <0.001). CONCLUSION: M/H ratio as a novel marker of inflammation seemed to be an independent predictor of ST in STEMI patients. FAU - Cetin, Elif Hande Ozcan AU - Cetin EH AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. FAU - Cetin, Mehmet Serkan AU - Cetin MS AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. FAU - Canpolat, Ugur AU - Canpolat U AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. FAU - Aydin, Selahattin AU - Aydin S AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. FAU - Topaloglu, Serkan AU - Topaloglu S AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. FAU - Aras, Dursun AU - Aras D AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. FAU - Aydogdu, Sinan AU - Aydogdu S AD - Turkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey. LA - eng PT - Journal Article DEP - 20151006 PL - England TA - Biomark Med JT - Biomarkers in medicine JID - 101312535 RN - 0 (Cholesterol, HDL) SB - IM MH - Cholesterol, HDL/*blood MH - *Electrocardiography MH - Female MH - Humans MH - Kaplan-Meier Estimate MH - Leukocyte Count MH - Male MH - Middle Aged MH - Monocytes/*cytology MH - Myocardial Infarction/*physiopathology/therapy MH - Percutaneous Coronary Intervention/*adverse effects MH - Prognosis MH - Stents/*adverse effects MH - Thrombosis/*blood/diagnosis/etiology OTO - NOTNLM OT - PCI OT - ST elevation myocardial infarction OT - inflammation OT - monocyte to HDL ratio OT - stent thrombosis EDAT- 2015/10/07 06:00 MHDA- 2016/08/10 06:00 CRDT- 2015/10/07 06:00 PHST- 2015/10/07 06:00 [entrez] PHST- 2015/10/07 06:00 [pubmed] PHST- 2016/08/10 06:00 [medline] AID - 10.2217/bmm.15.74 [doi] PST - ppublish SO - Biomark Med. 2015;9(10):967-77. doi: 10.2217/bmm.15.74. Epub 2015 Oct 6.