PMID- 26440433 OWN - NLM STAT- MEDLINE DCOM- 20160720 LR - 20220317 IS - 1878-4372 (Electronic) IS - 1360-1385 (Linking) VI - 20 IP - 10 DP - 2015 Oct TI - Illuminating Progress in Phytochrome-Mediated Light Signaling Pathways. PG - 641-650 LID - S1360-1385(15)00174-0 [pii] LID - 10.1016/j.tplants.2015.06.010 [doi] AB - Light signals regulate a plethora of plant responses throughout their life cycle, especially the red and far-red regions of the light spectrum perceived by the phytochrome family of photoreceptors. However, the mechanisms by which phytochromes regulate gene expression and downstream responses remain elusive. Several recent studies have unraveled the details on how phytochromes regulate photomorphogenesis. These include the identification of E3 ligases that degrade PHYTOCHROME INTERACTING FACTOR (PIF) proteins, key negative regulators, in response to light, a better view of how phytochromes inhibit another key negative regulator, CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1), and an understanding of why plants evolved multiple negative regulators to repress photomorphogenesis in darkness. These advances will surely fuel future research on many unanswered questions that have intrigued plant photobiologists for decades. CI - Copyright (c) 2015 Elsevier Ltd. All rights reserved. FAU - Xu, Xiaosa AU - Xu X AD - Department of Molecular Biosciences and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA. FAU - Paik, Inyup AU - Paik I AD - Department of Molecular Biosciences and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA. FAU - Zhu, Ling AU - Zhu L AD - Department of Molecular Biosciences and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA. FAU - Huq, Enamul AU - Huq E AD - Department of Molecular Biosciences and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address: huq@austin.utexas.edu. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Review PL - England TA - Trends Plant Sci JT - Trends in plant science JID - 9890299 RN - 0 (Arabidopsis Proteins) RN - 11121-56-5 (Phytochrome) RN - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis) RN - EC 2.3.2.27 (Ubiquitin-Protein Ligases) SB - IM MH - Arabidopsis/*genetics/physiology MH - Arabidopsis Proteins/*metabolism MH - Darkness MH - Light MH - *Light Signal Transduction MH - Phytochrome/*metabolism MH - Ubiquitin-Protein Ligases/*metabolism EDAT- 2015/10/07 06:00 MHDA- 2016/07/21 06:00 CRDT- 2015/10/07 06:00 PHST- 2015/04/29 00:00 [received] PHST- 2015/06/24 00:00 [revised] PHST- 2015/06/29 00:00 [accepted] PHST- 2015/10/07 06:00 [entrez] PHST- 2015/10/07 06:00 [pubmed] PHST- 2016/07/21 06:00 [medline] AID - S1360-1385(15)00174-0 [pii] AID - 10.1016/j.tplants.2015.06.010 [doi] PST - ppublish SO - Trends Plant Sci. 2015 Oct;20(10):641-650. doi: 10.1016/j.tplants.2015.06.010.