PMID- 26441443 OWN - NLM STAT- MEDLINE DCOM- 20170713 LR - 20171109 IS - 1558-2531 (Electronic) IS - 0018-9294 (Linking) VI - 63 IP - 6 DP - 2016 Jun TI - A New Feature-Enhanced Speckle Reduction Method Based on Multiscale Analysis for Ultrasound B-Mode Imaging. PG - 1178-91 LID - 10.1109/TBME.2015.2486042 [doi] AB - Effective speckle reduction in ultrasound B-mode imaging is important for enhancing the image quality and improving the accuracy in image analysis and interpretation. In this paper, a new feature-enhanced speckle reduction (FESR) method based on multiscale analysis and feature enhancement filtering is proposed for ultrasound B-mode imaging. In FESR, clinical features (e.g., boundaries and borders of lesions) are selectively emphasized by edge, coherence, and contrast enhancement filtering from fine to coarse scales while simultaneously suppressing speckle development via robust diffusion filtering. In the simulation study, the proposed FESR method showed statistically significant improvements in edge preservation, mean structure similarity, speckle signal-to-noise ratio, and contrast-to-noise ratio (CNR) compared with other speckle reduction methods, e.g., oriented speckle reducing anisotropic diffusion (OSRAD), nonlinear multiscale wavelet diffusion (NMWD), the Laplacian pyramid-based nonlinear diffusion and shock filter (LPNDSF), and the Bayesian nonlocal means filter (OBNLM). Similarly, the FESR method outperformed the OSRAD, NMWD, LPNDSF, and OBNLM methods in terms of CNR, i.e., 10.70 +/- 0.06 versus 9.00 +/- 0.06, 9.78 +/- 0.06, 8.67 +/- 0.04, and 9.22 +/- 0.06 in the phantom study, respectively. Reconstructed B-mode images that were developed using the five speckle reduction methods were reviewed by three radiologists for evaluation based on each radiologist's diagnostic preferences. All three radiologists showed a significant preference for the abdominal liver images obtained using the FESR methods in terms of conspicuity, margin sharpness, artificiality, and contrast, p<0.0001. For the kidney and thyroid images, the FESR method showed similar improvement over other methods. However, the FESR method did not show statistically significant improvement compared with the OBNLM method in margin sharpness for the kidney and thyroid images. These results demonstrate that the proposed FESR method can improve the image quality of ultrasound B-mode imaging by enhancing the visualization of lesion features while effectively suppressing speckle noise. FAU - Kang, Jinbum AU - Kang J FAU - Lee, Jae Young AU - Lee JY FAU - Yoo, Yangmo AU - Yoo Y LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20151002 PL - United States TA - IEEE Trans Biomed Eng JT - IEEE transactions on bio-medical engineering JID - 0012737 SB - IM MH - Algorithms MH - Humans MH - Image Interpretation, Computer-Assisted/*methods MH - Kidney/diagnostic imaging MH - Phantoms, Imaging MH - Signal-To-Noise Ratio MH - Thyroid Gland/diagnostic imaging MH - Ultrasonography/*methods EDAT- 2015/10/07 06:00 MHDA- 2017/07/14 06:00 CRDT- 2015/10/07 06:00 PHST- 2015/10/07 06:00 [entrez] PHST- 2015/10/07 06:00 [pubmed] PHST- 2017/07/14 06:00 [medline] AID - 10.1109/TBME.2015.2486042 [doi] PST - ppublish SO - IEEE Trans Biomed Eng. 2016 Jun;63(6):1178-91. doi: 10.1109/TBME.2015.2486042. Epub 2015 Oct 2.