PMID- 26446586 OWN - NLM STAT- MEDLINE DCOM- 20170111 LR - 20170112 IS - 1437-1588 (Electronic) IS - 1436-9990 (Linking) VI - 59 IP - 1 DP - 2016 Jan TI - [Multidrug-resistant bacteria in Germany. The impact of sources outside healthcare facilities]. PG - 113-23 LID - 10.1007/s00103-015-2261-z [doi] AB - BACKGROUND: Currently, there is an ongoing discussion about the question whether the emergence of multidrug-resistant microorganisms (MDRO) among humans is due to transfer of these bacteria from animals. OBJECTIVES: This review summarizes data on the occurrence of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) producing enterobacteria in animals and humans, and describes knowledge about transmission pathways. MATERIAL AND METHODS: After a scientific literature analysis, relevant articles were identified by screening of titles and abstracts, amended by publications of infection control authorities and the respective reference lists. RESULTS: MDRO are both transmitted in the nosocomial setting and are increasingly detected as sources of infection outside healthcare facilities. CONCLUSIONS: Due to new transmission pathways of MDRO an inter-disciplinary approach towards prevention is necessary, involving medical, pharmaceutical and veterinary expertise. FAU - Idelevich, Evgeny A AU - Idelevich EA AD - Institut fur Medizinische Mikrobiologie, Universitatsklinikum Munster, 48149, Munster, Deutschland. FAU - Lanckohr, Christian AU - Lanckohr C AD - Klinik fur Anasthesiologie, operative Intensivmedizin und Schmerztherapie, Universitatsklinikum Munster, Munster, Deutschland. FAU - Horn, Dagmar AU - Horn D AD - Apotheke, Universitatsklinikum Munster, Munster, Deutschland. FAU - Wieler, Lothar H AU - Wieler LH AD - Robert Koch-Institut, Berlin, Deutschland. AD - Institut fur Mikrobiologie und Tierseuchen, Freie Universitat Berlin, Berlin, Deutschland. AD - Fachgruppe Zoonosen, Deutschen Gesellschaft fur Hygiene und Mikrobiologie (DGHM), Munster, Deutschland. FAU - Becker, Karsten AU - Becker K AD - Institut fur Medizinische Mikrobiologie, Universitatsklinikum Munster, 48149, Munster, Deutschland. FAU - Kock, Robin AU - Kock R AD - Institut fur Medizinische Mikrobiologie, Universitatsklinikum Munster, 48149, Munster, Deutschland. robin.koeck@ukmuenster.de. AD - Fachgruppe Zoonosen, Deutschen Gesellschaft fur Hygiene und Mikrobiologie (DGHM), Munster, Deutschland. robin.koeck@ukmuenster.de. LA - ger PT - Journal Article PT - Review TT - Antibiotika-resistente Erreger in Deutschland. Die Rolle von nicht nosokomialen Ansteckungsquellen. PL - Germany TA - Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz JT - Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz JID - 101181368 RN - 0 (Anti-Bacterial Agents) SB - IM MH - Animals MH - Anti-Bacterial Agents/therapeutic use MH - Bacterial Infections/*drug therapy/*epidemiology/microbiology MH - Cross Infection/*drug therapy/*epidemiology/microbiology MH - Drug Resistance, Multiple, Bacterial/*drug effects MH - Evidence-Based Medicine MH - Germany/epidemiology MH - Health Facilities/statistics & numerical data MH - Humans MH - Prevalence MH - Risk Factors MH - Zoonoses/*epidemiology/microbiology/transmission OTO - NOTNLM OT - Antibiotics OT - Germany OT - Livestock OT - Pets OT - Zoonosis EDAT- 2015/10/09 06:00 MHDA- 2017/01/12 06:00 CRDT- 2015/10/09 06:00 PHST- 2015/10/09 06:00 [entrez] PHST- 2015/10/09 06:00 [pubmed] PHST- 2017/01/12 06:00 [medline] AID - 10.1007/s00103-015-2261-z [pii] AID - 10.1007/s00103-015-2261-z [doi] PST - ppublish SO - Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Jan;59(1):113-23. doi: 10.1007/s00103-015-2261-z.