PMID- 26455181
OWN - NLM
STAT- MEDLINE
DCOM- 20160302
LR  - 20181202
IS  - 1002-1892 (Print)
IS  - 1002-1892 (Linking)
VI  - 29
IP  - 1
DP  - 2015 Jan
TI  - [COMPARISON OF BIOLOGICAL DIFFERENCE BETWEEN BONE MARROW AND PLACENTA-DERIVED 
      MESENCHIMAL STEM CELLS IN HYPOXIA].
PG  - 103-7
AB  - OBJECTIVE: To comprehensively analyze and compare the biological difference 
      between bone marrow mesenchymal stem cells (BMSCs) and placenta-derived MSCs 
      (PMSCs) in hypoxia and to extend the knowledge for seed cells selection. METHODS: 
      The domestic and foreign related literature about the effects of hypoxia 
      microenvironment on proliferation, apoptosis, differentiation, paracrine 
      secretion, migration, and homing ability of BMSCs and PMSCs were summarized and 
      analysed. RESULTS: PMSCs proliferated much faster and more sensitive to the 
      hypoxia than BMSCs; in addition, PMSCs showed stronger survivability. Similar to 
      BMSCs, PMSCs can home to hypoxic-ischemic tissues efficiently, secrete a lot of 
      growth factors and differentiate into tissue-specific cells to stimulate tissue 
      regeneration. CONCLUSION: PMSCs as the seed cells will have broad application 
      prospects in the regenerative medicine.
FAU - Xia, Bo
AU  - Xia B
FAU - Tan, Meiyun
AU  - Tan M
LA  - chi
PT  - Comparative Study
PT  - Journal Article
PL  - China
TA  - Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
JT  - Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = 
      Chinese journal of reparative and reconstructive surgery
JID - 9425194
SB  - IM
MH  - Bone Marrow Cells/*cytology
MH  - *Cell Differentiation
MH  - *Cell Hypoxia
MH  - Female
MH  - Humans
MH  - Hypoxia
MH  - *Mesenchymal Stem Cells
MH  - Placenta/*cytology
MH  - Pregnancy
MH  - Regenerative Medicine
MH  - Stem Cells
EDAT- 2015/10/13 06:00
MHDA- 2016/03/05 06:00
CRDT- 2015/10/13 06:00
PHST- 2015/10/13 06:00 [entrez]
PHST- 2015/10/13 06:00 [pubmed]
PHST- 2016/03/05 06:00 [medline]
PST - ppublish
SO  - Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2015 Jan;29(1):103-7.