PMID- 26456063 OWN - NLM STAT- MEDLINE DCOM- 20170929 LR - 20170929 IS - 1532-8414 (Electronic) IS - 1071-9164 (Linking) VI - 22 IP - 8 DP - 2016 Aug TI - Timed Up and Go Test: A Reliable and Valid Test in Patients With Chronic Heart Failure. PG - 646-50 LID - S1071-9164(15)01124-0 [pii] LID - 10.1016/j.cardfail.2015.09.018 [doi] AB - BACKGROUND: The timed up and go test (TUGT) is a short-duration functional test frequently used in rehabilitation settings as a measure of balance and mobility. Reliability and validity for patients with chronic heart failure (CHF) has yet to be determined. This prospective cohort study aimed to determine test-retest reliability of the TUGT in patients with CHF, relationships between the TUGT and other variables, including functional tests, and predictors of the TUGT. METHODS AND RESULTS: This was a secondary analysis of data collected in a multicenter randomized controlled trial of exercise training in recently hospitalized patients with heart failure (EJECTION-HF). The TUGT was conducted twice at baseline to determine reliability. Assessments were compared with 6-minute walk distance (6MWD), 10-m walk test time, and other clinical variables. Intraclass correlation coefficient (ICC) was used to determine test-retest reliability and correlations for relationships with other variables. A multiple regression was used to identify predictors of the TUGT. In 278 participants (mean age 62 years), the TUGT demonstrated excellent within-day test-retest reliability (ICC 0.93). A shorter (better) TUGT time was associated with longer 6MWD (r = -0.81; P < .001) and shorter 10-m walk test time (rs = 0.80; P < .001). Best predictors of the TUGT were 6MWD and age, which accounted for 66% of the variance. CONCLUSIONS: The TUGT appears to be a reliable and valid functional measurement in patients with CHF. CI - Crown Copyright (c) 2015. Published by Elsevier Inc. All rights reserved. FAU - Hwang, Rita AU - Hwang R AD - Department of Physiotherapy, Princess Alexandra Hospital, Metro South Health, Brisbane, Queensland, Australia; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia. Electronic address: r.hwang@uq.net.au. FAU - Morris, Norman R AU - Morris NR AD - Menzies Health Institute Queensland and School of Allied Health Sciences, Griffith University, Gold Coast, Queensland, Australia. FAU - Mandrusiak, Allison AU - Mandrusiak A AD - School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia. FAU - Mudge, Alison AU - Mudge A AD - Internal Medicine and Aged Care, Royal Brisbane and Women's Hospital, Queensland, Australia; School of Medicine, The University of Queensland, Brisbane, Queensland, Australia. FAU - Suna, Jessica AU - Suna J AD - Internal Medicine Research Unit, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. FAU - Adsett, Julie AU - Adsett J AD - Heart Failure Service, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. FAU - Russell, Trevor AU - Russell T AD - School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia. LA - eng PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial DEP - 20151009 PL - United States TA - J Card Fail JT - Journal of cardiac failure JID - 9442138 SB - IM MH - Exercise Test/*methods MH - Exercise Therapy/*methods MH - Exercise Tolerance/*physiology MH - Female MH - Follow-Up Studies MH - Heart Failure/diagnosis/physiopathology/*rehabilitation MH - Humans MH - Male MH - Middle Aged MH - Reproducibility of Results MH - Time Factors MH - Treatment Outcome MH - Walking/*physiology OTO - NOTNLM OT - Exercise test OT - cardiac failure OT - functional capacity OT - outcome assessment EDAT- 2015/10/13 06:00 MHDA- 2017/09/30 06:00 CRDT- 2015/10/13 06:00 PHST- 2015/08/29 00:00 [received] PHST- 2015/08/29 00:00 [revised] PHST- 2015/09/25 00:00 [accepted] PHST- 2015/10/13 06:00 [entrez] PHST- 2015/10/13 06:00 [pubmed] PHST- 2017/09/30 06:00 [medline] AID - S1071-9164(15)01124-0 [pii] AID - 10.1016/j.cardfail.2015.09.018 [doi] PST - ppublish SO - J Card Fail. 2016 Aug;22(8):646-50. doi: 10.1016/j.cardfail.2015.09.018. Epub 2015 Oct 9.